지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 649 - 654 (6page)
이용수
초록· 키워드
오류제보하기
ObjectiveaaWe aimed to investigate the long-term effects of atomoxetine on growth in Korean children and adolescents with attentiondeficit/ hyperactivity disorder (ADHD). MethodsaaThe medical records of 82 subjects (mean age, 9.0±2.0 years; 64 boys) with ADHD treated with atomoxetine for at least 1 year at the Department of Psychiatry at Asan Medical Center were retrospectively reviewed. Height and weight data were prospectively obtained and retrospectively gathered and converted to age- and gender-corrected z scores using norms from Korean youths. Growth changes were analyzed using random coefficients models with changes in height or weight z scores as the dependent variables. ResultsaaHeight z scores significantly decreased during the treatment period (β=-0.054, p=0.024). Height z scores decreased during the 1st year of treatment (β=-0.086, p=0.003), but did not change after the 1st year. Weight z scores did not change significantly during treatment (β=0.004, p=0.925). ConclusionaaOur results suggest that long-term atomoxetine treatment may be associated with deficits in height growth in Korean youths, although this effect was minor and tended to be attenuated over the first year. Because of the limitations of this study such as retrospective design and selection bias, further prospective studies are needed.
목차
등록된 정보가 없습니다.
참고문헌 (15)
참고문헌 신청
Hammerness P / 2009 / Atomoxetine for the treatment of attention-deficit/hyperactivity disorder in children and adolescents: a review / Neuropsychiatr Dis Treat 5:215~226
Spencer TJ / 2007 / Effects of atomoxetine on growth in children with attentiondeficit/hyperactivity disorder following up to five years of treatment / J Child Adolesc Psychopharmacol 17:689~699
Spencer TJ / 2005 / Effects of atomoxetine on growth after 2-year treatment among pediatric patients with attention-deficit/hyperactivity disorder / Pediatrics 116:e74~e80
Kratochvil CJ / 2006 / Effects of long-term atomoxetine treatment for young children with attention-deficit/hyperactivity disorder / J Am Acad Child Adolesc Psychiatry 45:919~927
Donnelly C / 2009 / Safety and tolerability of atomoxetine over 3 to 4 years in children and adolescents with ADHD / J Am Acad Child Adolesc Psychiatry 48:176~185
Spencer TJ / 2007 / Effects of atomoxetine on growth in children with attentiondeficit/hyperactivity disorder following up to five years of treatment / J Child Adolesc Psychopharmacol 17:689~699
Spencer TJ / 2005 / Effects of atomoxetine on growth after 2-year treatment among pediatric patients with attention-deficit/hyperactivity disorder / Pediatrics 116:e74~e80
Kratochvil CJ / 2006 / Effects of long-term atomoxetine treatment for young children with attention-deficit/hyperactivity disorder / J Am Acad Child Adolesc Psychiatry 45:919~927
Donnelly C / 2009 / Safety and tolerability of atomoxetine over 3 to 4 years in children and adolescents with ADHD / J Am Acad Child Adolesc Psychiatry 48:176~185
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