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지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2009.1
- 수록면
- 85 - 95 (11page)
이용수
초록· 키워드
오류제보하기
Objective: The objective of this study was to identify patterns of brain activation elicited by erotic visual stimuli in patients treated with either Selective Serotonin Reuptake Inhibitors (SSRIs) or mirtazipine.
MethodsaaNine middle-aged men with major depressive disorder treated with an SSRI and ten middle-aged men with major depressive disorder treated with mirtazapine completed the trial. Ten subjects with no psychiatric illness were included as a control group. We conducted functional brain magnetic resonance imaging (fMRI) while a film alternatively played erotic and non-erotic contents for 14 minutes and 9 seconds.
Results: The control group showed activation in the occipitotemporal area, anterior cingulate gyrus, insula, orbitofrontal cortex, and caudate nucleus. For subjects treated with SSRIs, the intensity of activity in these regions was much lower compared to the control group. Intensity of activation in the group treated with mirtazapine was less than the control group but grea-ter than those treated with SSRIs. Using subtraction analysis, the SSRI group showed
significantly lower activation than the mirtazapine group in the anterior cingulate gyrus and the caudate nucleus.
Conclusion: Our study suggests that the different rates of sexual side effects between the patients in the SSRI-treated group and the mirtazapine-treated group may be due to different effects on brain activation.
목차
등록된 정보가 없습니다.
참고문헌 (27)
참고문헌 신청
Arnow BA / 2002 / Brain activation and sexual arousal in healthy, heterosexual males / Brain 125 : 1014 ~ 1023
Bruijn JA / 1996 / A double-blind, fixed blood-level study comparing mirtazapine with imipramine in depressed in-patients / Psychopharmacology 127 : 231 ~ 237
Ferretti A / 2005 / Dynamics of male sexual arousal: distinct components of brain activation revealed by fMRI / Neuroimage 26 : 1086 ~ 1096
First MB / 1997 / Structured Clinical Interview for DSM-IV-Clinician Version (SCID-CV) / American Psychiatric Press
Garrett AS / 2001 / Timecourse of the subjective emotional response to aversive pictures: relevance to fMRI studies / Psychiatry Res 108 : 39 ~ 48
Bruijn JA / 1996 / A double-blind, fixed blood-level study comparing mirtazapine with imipramine in depressed in-patients / Psychopharmacology 127 : 231 ~ 237
Ferretti A / 2005 / Dynamics of male sexual arousal: distinct components of brain activation revealed by fMRI / Neuroimage 26 : 1086 ~ 1096
First MB / 1997 / Structured Clinical Interview for DSM-IV-Clinician Version (SCID-CV) / American Psychiatric Press
Garrett AS / 2001 / Timecourse of the subjective emotional response to aversive pictures: relevance to fMRI studies / Psychiatry Res 108 : 39 ~ 48
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