지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한소아알레르기호흡기학회 Allergy Asthma & Respiratory Diseases Allergy Asthma & Respiratory Diseases 제5권 제1호
- 발행연도
- 2017.1
- 수록면
- 52 - 55 (4page)
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초록· 키워드
오류제보하기
Acute generalized exanthematous pustulosis (AGEP) is a severe and rare disease usually related to drug eruption. AGEP is induced by drugs in over 90% of cases with antibiotics being the most common. It is characterized by a fever and a pustular eruption on erythematous skin with acute onset and without follicular localization. Acetaminophen is commonly used as an antipyretic and analgesic.
Acetaminophen has been reported to be an uncommon cause of AGEP. We report a 79-year-old woman presenting with fever and erythematous maculopapular eruptions on the trunk with sterile pustules arising upon the use of acetaminophen for back pain. Leukocytosis and elevated C-reactive protein levels were noted on the laboratory examination. The histopathological examination of the skin biopsy specimen showed intraepidermal pustule formation with superficial perivascular lymphocytic infiltration, including eosinophils, and extensive red blood cell extravasation. The lesions were resolved with discontinuation of acetaminophen and use of systemic corticosteroid. We report a case of AGEP probably caused by acetaminophen.
목차
등록된 정보가 없습니다.
참고문헌 (13)
참고문헌 신청
Bachot N / 2003 / Differential diagnosis of severe cutaneous drug eruptions / Am J Clin Dermatol 4 : 561 ~ 572
Bomarrito L / 2013 / A case of acute generalized exanthematous pustulosis due to amoxicillin-clavulanate with multiple positivity to beta-lactam patch testing / Eur Ann Aller
Britschgi M / 2001 / T-cell involvement in drug-induced acute generalized exanthematous pustulosis / J Clin Invest 107 : 1433 ~ 1441
Brockow K / 2013 / Skin test concentrations for systemically administered drugs: an ENDA/EAACI Drug Allergy Interest Group position paper / Allergy 68 : 702 ~ 712
Halevy S / 2000 / Acute generalized exanthematous pustulosis associated with polysensitivity to paracetamol and bromhexine: the diagnostic role of in vitro interferon-gamma
Bomarrito L / 2013 / A case of acute generalized exanthematous pustulosis due to amoxicillin-clavulanate with multiple positivity to beta-lactam patch testing / Eur Ann Aller
Britschgi M / 2001 / T-cell involvement in drug-induced acute generalized exanthematous pustulosis / J Clin Invest 107 : 1433 ~ 1441
Brockow K / 2013 / Skin test concentrations for systemically administered drugs: an ENDA/EAACI Drug Allergy Interest Group position paper / Allergy 68 : 702 ~ 712
Halevy S / 2000 / Acute generalized exanthematous pustulosis associated with polysensitivity to paracetamol and bromhexine: the diagnostic role of in vitro interferon-gamma
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