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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한병리학회 Journal of Pathology and Translational Medicine Journal of Pathology and Translational Medicine 제42권 제6호
- 발행연도
- 2008.1
- 수록면
- 389 - 392 (4page)
이용수
초록· 키워드
오류제보하기
Large cell neuroendocrine carcinoma (LCNEC) of the uterine cervix is a rare and aggressive malignancy. We report a case of uterine cervical LCNEC concurrent with high grade squamous intraepithelial neoplasia (HG-SIN). The LCNEC expressed chromogranin A and thyroid transcription factor 1 (TTF1). The HG-SIN was negative for these markers. Human papillomavirus (HPV) type 18 was positive in LCNEC whereas both type 16 and 18 were positive in HG-SIN by nested polymerase chain reaction. This case showed TTF1 positivity nonetheless diagnosed as a primary uterine cervical LCNEC confirmed by the detection of HPV genome within the tumor. It is critical to recognize LCNEC of the uterine cervix even in the small biopsy specimen because it is a distinctive clinicopathological entity with highly aggressive behavior and unfavorable outcome.
목차
등록된 정보가 없습니다.
참고문헌 (7)
참고문헌 신청
Dikmen Y / 2004 / Large cell neuroendocrine carcinoma of the uterine cervix: a report of a case and review of the literature / Arch Gynecol Obstet 270 : 185 ~ 188
Gilks CB / 1997 / Large cell carcinoma of the uterine cervix: a clinicopathologic study of 12 cases / Am J Surg Pathol 21 : 905 ~ 914
Grayson W / 2002 / Detection of human papillomavirus in large cell neuroendocrine carcinoma of the uterine cervix: a study of 12 cases / J Clin Pathol 55 : 108 ~ 114
Kim KK / 2004 / A case of mixed type large cell neuroendocrine carcinoma of the uterine cervix / Korean J Obstet Gynecol 47 : 2494 ~ 2498
McCluggage WG / 2007 / Large cell neuroendocrine carcinoma of the uterine cervix exhibiting TTF1 immunoreactivity / Histopathology 51 : 405 ~ 407
Gilks CB / 1997 / Large cell carcinoma of the uterine cervix: a clinicopathologic study of 12 cases / Am J Surg Pathol 21 : 905 ~ 914
Grayson W / 2002 / Detection of human papillomavirus in large cell neuroendocrine carcinoma of the uterine cervix: a study of 12 cases / J Clin Pathol 55 : 108 ~ 114
Kim KK / 2004 / A case of mixed type large cell neuroendocrine carcinoma of the uterine cervix / Korean J Obstet Gynecol 47 : 2494 ~ 2498
McCluggage WG / 2007 / Large cell neuroendocrine carcinoma of the uterine cervix exhibiting TTF1 immunoreactivity / Histopathology 51 : 405 ~ 407
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