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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한병리학회 Journal of Pathology and Translational Medicine Journal of Pathology and Translational Medicine 제51권 제6호
- 발행연도
- 2017.1
- 수록면
- 588 - 593 (6page)
이용수
초록· 키워드
오류제보하기
Ependymoma is the third most common pediatric primary brain tumor. Ependymomas are categorized according to their locations and genetic abnormalities, and these two parameters are important prognostic factors for patient outcome. For supratentorial (ST) ependymomas, RELA fusion-positive ependymomas show a more aggressive behavior than YAP1 fusion-positive ependymomas. Extracranial metastases of intra-axial neuroepithelial tumors are extremely rare. In this paper, we report a case of aggressive anaplastic ependymoma arising in the right frontoparietal lobe, which had genetically 1q25 gain, CDKN2A homozygous deletion, and L1CAM overexpression. The patient was a 10-year-old boy who underwent four times of tumor removal and seven times of gamma knife surgery. Metastatic loci were scalp and temporalis muscle overlying primary operation site, lung, liver, buttock, bone, and mediastinal lymph nodes. He had the malignancy for 10 years and died. This tumor is a representative case of RELA fusion-positive ST ependymoma, showing aggressive behavior.
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등록된 정보가 없습니다.
참고문헌 (20)
참고문헌 신청
Chao MM / 2011 / Isolated extracranial recurrence of anaplastic ependymoma / Pediatr Blood Cancer 56 : 317 ~ 318
Chhabda S / 2016 / The 2016 World Health Organization Classification of tumours of the central nervous system: what the paediatric neuroradiologist needs to know / Quant Imag
Davis MJ / 2011 / Extraventricular anaplastic ependymoma with metastasis to scalp and neck / J Neurooncol 104 : 599 ~ 604
Ernestus RI / 1996 / Prognostic relevance of localization and grading in intracranial ependymomas of childhood / Childs Nerv Syst 12 : 522 ~ 526
Ferracini R / 1984 / A cerebral ependymoma with extracranial metastases / Tumori 70 : 389 ~ 392
Chhabda S / 2016 / The 2016 World Health Organization Classification of tumours of the central nervous system: what the paediatric neuroradiologist needs to know / Quant Imag
Davis MJ / 2011 / Extraventricular anaplastic ependymoma with metastasis to scalp and neck / J Neurooncol 104 : 599 ~ 604
Ernestus RI / 1996 / Prognostic relevance of localization and grading in intracranial ependymomas of childhood / Childs Nerv Syst 12 : 522 ~ 526
Ferracini R / 1984 / A cerebral ependymoma with extracranial metastases / Tumori 70 : 389 ~ 392
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