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자료유형
학술저널
저자정보
Yuh, Woon Tak (Department of Neurosurgery, Seoul National University Hospital) Chung, Chun Kee (Department of Neurosurgery, Seoul National University Hospital) Park, Sung-Hye (Department of Pathology, Seoul National University Hospital, Seoul National University College of Medicine) Kim, Ki-Jeong (Department of Neurosurgery, Seoul National University Bundang Hospital) Lee, Sun-Ho (Department of Neurosurgery, Samsung Medical Center, Sungkyunkwan University School of Medicine) Kim, Kyoung-Tae (Department of Neurosurgery, Kyungpook National University Hospital)
저널정보
대한신경외과학회 대한신경외과학회지 대한신경외과학회지 제61권 제2호
발행연도
2018.1
수록면
233 - 242 (10page)

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Objective : A spinal cord subependymoma is an uncommon, indolent, benign spinal cord tumor. It is radiologically similar to a spinal cord ependymoma, but surgical findings and outcomes differ. Gross total resection of the tumor is not always feasible. The present study was done to determine the clinical, radiological and pathological characteristics of spinal cord subependymomas. Methods : We retrospectively reviewed the medical records of ten spinal cord subependymoma patients (M : F=4 : 6; median 38 years; range, 21-77) from four institutions. Results : The most common symptoms were sensory changes and/or pain in eight patients, followed by motor weakness in six. The median duration of symptoms was 9.5 months. Preoperative radiological diagnosis was ependymoma in seven and astrocytoma in three. The tumors were located eccentrically in six and were not enhanced in six. Gross total resection of the tumor was achieved in five patients, whereas subtotal or partial resection was inevitable in the other five patients due to a poor dissection plane. Adjuvant radiotherapy was performed in two patients. Neurological deterioration occurred in two patients; transient weakness in one after subtotal resection and permanent weakness after gross total resection in the other. Recurrence or regrowth of the tumor was not observed during the median 31.5 months follow-up period (range, 8-89). Conclusion : Spinal cord subependymoma should be considered when the tumor is located eccentrically and is not dissected easily from the spinal cord. Considering the rather indolent nature of spinal cord subependymomas, subtotal removal without the risk of neurological deficit is another option.

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