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Hepatoid Carcinoma of the Pancreas Presenting as Acute Pancreatitis
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급성 췌장염으로 내원한 간세포양 암종 1예

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Type
Academic journal
Author
Journal
The Korean Association Of Internal Medicine 대한내과학회지 대한내과학회지 제93권 제4호 KCI Candidated Journals
Published
2018.1
Pages
387 - 392 (6page)

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Hepatoid Carcinoma of the Pancreas Presenting as Acute Pancreatitis
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Abstract· Keywords

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Hepatoid carcinoma is extrahepatic neoplasm showing similar morphologic, immunohistochemical features with hepatocellular carcinoma. It’s a very rare disease and has been reported most frequently in the stomach. Herein, we report a case of hepatoid carcinoma of pancreas presented with acute pancreatitis. The hepatoid carcinoma was diagnosed by his needle biopsy specimen and it showed pleomorphic nuclei and predominantly eosinophilic and occasionally clear cytoplasm in hematoxylin and eosin staining, and positive for HepPar-1 and cytokeratin 19 in immunohistochemical staining. Surgical treatment seems to be the best choice, if possible. However, there is no standard regimen for palliative chemotherapy. In our case, the patient was treated with 5-Fluorouracil (5-FU), folinic acid, irinotecan, oxaliplatin (FOLFIRINOX). The response was stable disease up to 4 month of follow up.
#Hepatoid carcinoma #Pancreas #Chemotherapy

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References (10)

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Marchegiani G / 2013 / Pancreatic hepatoid carcinoma: a review of the literature / Dig Surg 30:425~433 Crossref Ishikura H / 1985 / An AFP-producing gastric carcinoma with features of hepatic differentiation. A case report / Cancer 56:840~848 Crossref Kuo PC / 2015 / Hepatoid carcinoma of the pancreas / World J Surg Oncol 13:185 Crossref Hruban RH / 1987 / A neoplasm with pancreatic and hepatocellular differentiation presenting with subcutaneous fat necrosis / Am J Clin Pathol 88:639~645 Crossref 오현종 / 2006 / 췌장에 발생한 간세포양 암종 1예 / 대한소화기학회지 47(5):389~393 google schola

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