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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2008.1
- 수록면
- 213 - 216 (4page)
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초록· 키워드
오류제보하기
Continentalic acid (CA, (-)-pimara-8(14), 15-diene-19-oic
acid) was isolated from the roots of Aralia cordata
(Araliaceae) using bioassay-guided fractionation of a crude
chloroform extract. The antibacterial activity of CA against
Enterococcus faecalis and Enterococcus gallinarium was
estimated by determining minimum inhibitory concentrations
(MICs) and minimum bactericidal concentrations
(MBCs). CA exhibited potent activity against standard
vancomycin-resistant enterococci (VRE) and vancomycinsusceptible
enterococci (VSE), with MICs and MBCs values
between 4 and 8 μg/mL and 4 and 16 μg/mL, respectively.
This compound exhibited potent activity against strains of
VRE, which are highly resistant to clinically useful
antibiotics. These findings suggest that continentalic acid
may be useful in controlling enterococcal infection.
목차
등록된 정보가 없습니다.
참고문헌 (20)
참고문헌 신청
American Society for Microbiology (ASM) Task force on antibiotic resistance / 1995 / Report of the ASM task force on antibiotic resistance / Antimicrobial Agents and Chemothe
Colombo AP / 1998 / Clinical and microbiological features of refractory periodontitis subjects / Journal of Clinical Periodontology? 25 : 169 ~ 180
Dahlen G / 2000 / Identification and antimicrobial susceptibility of enterococci isolated from the root canal / Oral Microbiology and Immunology 15 : 309 ~ 312
Dang NH / 2005 / Inhibitory constituents against cyclooxygenases from Aralia cordata Thunb / Archives of Pharmacal Research? 28 : 28 ~ 33
Davis J / 1994 / Inactivation of antibiotics and the dissemination of resistance genes / Science 264 : 375 ~ 381
Colombo AP / 1998 / Clinical and microbiological features of refractory periodontitis subjects / Journal of Clinical Periodontology? 25 : 169 ~ 180
Dahlen G / 2000 / Identification and antimicrobial susceptibility of enterococci isolated from the root canal / Oral Microbiology and Immunology 15 : 309 ~ 312
Dang NH / 2005 / Inhibitory constituents against cyclooxygenases from Aralia cordata Thunb / Archives of Pharmacal Research? 28 : 28 ~ 33
Davis J / 1994 / Inactivation of antibiotics and the dissemination of resistance genes / Science 264 : 375 ~ 381
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Vancomycin resistant enterococci (VRE) isolates from human and animals
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독활로부터 분리한 continentalic acid의 항치아우식 활성
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2009 .01
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Genetic Characterization of Vancomycin-Resistant Enterococci from Raw Milk
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Inhibitory Effect of Continentalic Acid from Aralia continentalis on Streptococcus mutans Biofilm
International Journal of Oral Biology
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