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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2008.1
- 수록면
- 45 - 50 (6page)
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초록· 키워드
오류제보하기
Treponema denticola is the best studied oral spirochete
and numerous studies have shown that it is strongly
associated with periodontitis and expresses several putative
virulence factors. In this study, we report on a surface
protein of T. denticola, Td92, which is homologous to Tp92
of Treponema pallidum, an agent of syphilis. Immunofluorescence
assay and immunogold labeling with anti-
Td92 Ab revealed that Td92 had surface-exposed epitopes.
And Td92 was capable of binding to fibronectin and KB
cells, an oral epithelial cell line. In addition, Td92 could
enter the KB cells. These results indicate that Td92 is a
fibronectin-binding protein which can bind to and internalize
into the host cells, facilitating the virulence of T.
denticola.
목차
등록된 정보가 없습니다.
참고문헌 (20)
참고문헌 신청
Batista Da Silva, A. P. / 2004 / The major outer sheath protein of Treponema denticola inhibits the binding step of collagen phagocytosis in fibroblasts / Cellular Microbiolo
Cameron C. E. / 2000 / Opsonic potential, protective capacity, and sequence conservation of the Treponema pallidum subspecies pallidum Tp9 / Journal of Infectious Diseases 18
Chi, B. / 2003 / Role of dentilisin in Treponema denticola epithelial cell layer penetration / Research in Microbiology 154 : 637 ~ 643
Chia, J. S. / 2000 / Identification of a fibronectin binding protein from Streptococcus mutans / Infection and Immunity : 1864 ~ 1870
Edwards, A. M. / 2005 / Binding properties and adhesion-mediating regions of the major sheath protein of Treponema denticola ATCC 35405 / Infection and Immunity 73 : 2891 ~ 2
Cameron C. E. / 2000 / Opsonic potential, protective capacity, and sequence conservation of the Treponema pallidum subspecies pallidum Tp9 / Journal of Infectious Diseases 18
Chi, B. / 2003 / Role of dentilisin in Treponema denticola epithelial cell layer penetration / Research in Microbiology 154 : 637 ~ 643
Chia, J. S. / 2000 / Identification of a fibronectin binding protein from Streptococcus mutans / Infection and Immunity : 1864 ~ 1870
Edwards, A. M. / 2005 / Binding properties and adhesion-mediating regions of the major sheath protein of Treponema denticola ATCC 35405 / Infection and Immunity 73 : 2891 ~ 2
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