지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.1
- 수록면
- 8 - 13 (6page)
이용수
초록· 키워드
오류제보하기
Background: Inflammation is an important underlying mechanism in the pathogenesis of atherosclerosis, and an elevated resting heart rate underlies the process of atherosclerotic plaque formation. We hypothesized an associa-tion between resting heart rate and subclinical inflammation.Methods: Resting heart rate was recorded at baseline in the KoGES-ARIRANG (Korean Genome and Epidemiology Study on Atherosclerosis Risk of Rural Areas in the Korean General Population) cohort study, and was then divided into quartiles. Subclinical inflammation was measured by white blood cell count and high-sensitivity C-reactive protein. We used progressively adjusted regression models with terms for muscle mass, body fat proportion, and adiponectin in the fully adjusted models. We examined inflammatory markers as both continuous and categorical variables, using the clinical cut point of the highest quartile of white blood cell count (≥7,900/mm3) and ≥3 mg/dL for high-sensitivity C-reactive protein.Results: Participants had a mean age of 56.3±8.1 years and a mean resting heart rate of 71.4±10.7 beats/min; 39.1% were men. In a fully adjusted model, an increased resting heart rate was significantly associated with a higher white blood cell count and higher levels of high-sensitivity C-reactive protein in both continuous (P for trend <0.001) and categorical (P for trend <0.001) models.Conclusion: An increased resting heart rate is associated with a higher level of subclinical inflammation among healthy Korean people.
목차
등록된 정보가 없습니다.
참고문헌 (30)
참고문헌 신청
Bernik TR / 2002 / Pharmacological stimulation of the cholinergic antiinflammatory pathway / J Exp Med 195:781~788
Chiu JJ / 2009 / Vascular endothelial responses to altered shear stress : pathologic implications for atherosclerosis / Ann Med 41:19~28
Himburg HA / 2007 / Frequency-dependent response of the vascular endothelium to pulsatile shear stress / Am J Physiol Heart Circ Physiol 293:H645~H653
De Keulenaer GW / 1998 / Oscillatory and steady laminar shear stress differentially affect human endothelial redox state : role of a superoxideproducing NADH oxidase / Circ Res 82:1094~1101
Walpola PL / 1995 / Expression of ICAM-1 and VCAM-1 and monocyte adherence in arteries exposed to altered shear stress / Arterioscler Thromb Vasc Biol 15:2~10
Chiu JJ / 2009 / Vascular endothelial responses to altered shear stress : pathologic implications for atherosclerosis / Ann Med 41:19~28
Himburg HA / 2007 / Frequency-dependent response of the vascular endothelium to pulsatile shear stress / Am J Physiol Heart Circ Physiol 293:H645~H653
De Keulenaer GW / 1998 / Oscillatory and steady laminar shear stress differentially affect human endothelial redox state : role of a superoxideproducing NADH oxidase / Circ Res 82:1094~1101
Walpola PL / 1995 / Expression of ICAM-1 and VCAM-1 and monocyte adherence in arteries exposed to altered shear stress / Arterioscler Thromb Vasc Biol 15:2~10
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Night shift work and inflammatory markers in male workers aged 20–39 in a display manufacturing company
대한직업환경의학회지
2016 .09
-
건강검진 수검자에서 안정 시 심박수와 경계성 발목상완지수의연관성
Korean Journal of Family Practice
2019 .01
-
APOE Polymorphism Is Associated with C-reactive Protein Levels but Not with White Blood Cell Count: Dong-gu Study and Namwon Study
Journal of Korean Medical Science
2015 .01
-
한국 40세 이상 성인의 치주질환, 잔존 치아 수와 고감도 C-반응성 단백의 연관성: 2015 국민건강영양조사 제6기 자료
한국치위생학회지
2020 .01
-
Joint Effect of Cigarette Smoking and Body Mass Index on White Blood Cell Count in Korean Adults
Korean Journal of Family Medicine
2017 .01
-
Annual Report of the Korean Association of External Quality Assessment Service on Routine Hematology (2018)
Journal of Laboratory Medicine And Quality Assurance
2019 .01
-
Occupational and Leisure-time Physical Activity differentially affect High-sensitivity C-Reactive Protein among Korean adults
대한직업환경의학회 학술대회 논문집
2020 .11
-
Clinical Usefulness of Serum Uric Acid and Resting Heart Rate in the Diagnosis of Metabolic Syndrome in Korean Adults
대한의생명과학회지
2017 .06
-
Functional roles and mechanisms of ginsenosides from Panax ginseng in atherosclerosis
Journal of Ginseng Research
2021 .01
-
Protein
대한외과학회 학술대회 초록집
2016 .11
-
Slow Heart Rate Recovery Is Associated with Increased Exercise-induced Arterial Stiffness in Normotensive Patients without Overt Atherosclerosis
Journal of Cardiovascular Imaging
2019 .01
-
Subclinical Atherosclerosis in Patients with Cushing Syndrome: Evaluation with Carotid Intima-Media Thickness and Ankle-Brachial Index
Endocrinology and Metabolism
2015 .01
-
Decrease Rate of C-reactive protein following gastric cancer resection as a reliable discharge indicator
대한외과학회 학술대회 초록집
2017 .11
-
Development of Advanced Atherosclerotic Plaque by Injection of Inflammatory Proteins in a Rabbit Iliac Artery Model
Yonsei Medical Journal
2016 .01
-
The Stability of Blood Gas Parameters Depends on Leukocyte Counts
Annals of Laboratory Medicine
2021 .09
-
Roles of immune cell in the cardiovascular diseases
한국실험동물학회 학술발표대회 논문집
2021 .07
-
The Relationship between Subclinical Thyroid Disease and Cardiovascular Disease Risk Score in Koreans
Journal of Korean Medical Science
2017 .01
-
Moonlighting Activity of Secreted Inflammation- Regulatory Proteins
Yonsei Medical Journal
2018 .01
-
High-Sensitivity C-Reactive Protein and Risks of All-Cause and Cause-Specific Mortality in a Japanese Population
Asian Pacific journal of cancer prevention : APJCP
2016 .01
-
Connect medical education practices and research in Asia with the rest of world
Korean Journal of Medical Education
2017 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0