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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 316 - 322 (7page)
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초록· 키워드
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Background: This study examined the differences in factors associated with albuminuria according to gender and comorbidities of hypertension (HTN) and diabetes mellitus (DM).
Methods: We included 3,859 participants aged 20 to 79 years (55% female) from the 5th Korea National Health and Nutrition Examination Survey. Participants were excluded if they took antihypertensive or anti-diabetic medication, had chronic renal failure, had malignant tumor, were pregnant or menstruating during the health examination, or had missing urine albumin data. Albuminuria was defined by the participant’s urine albumin-creatinine ratio (uACR). Relationships between dependent and independent variables were analyzed using the Pearson’s correlation test and simple linear regression. Due to possible muticollinearity, multiple linear regression analysis was used to determine whether the association between the dependent and independent variables of interest remained significant after adjustment for other potentially confounding independent variables.
Results: The variables significantly correlated with uACR were different between the genders and between subjects with HTN or DM as a comorbidity. In the multiple linear regression models, hemoglobin A1c (P=0.01) was positively associated with uACR in men without HTN and DM. In men with HTN or DM, systolic blood pressure and fasting glucose (P<0.01) were positively associated with uACR. In women with HTN or DM, waist circumference (P=0.011) and gamma-glutamyl transpeptidase (P<0.001) were positively correlated with uACR (P<0.05) and glucose level (P=0.019) was negatively correlated with uACR.
Conclusion: The study suggested factors correlated with albuminuria were different for men and women according to comorbidities such as HTN and DM.
목차
등록된 정보가 없습니다.
참고문헌 (21)
참고문헌 신청
Ahonen T / 2012 / Sex differences in the association of adiponectin and low-grade inflammation with changes in the body mass index from youth to middle age / Gend Med 9 : 1
Arnlov J / 2005 / Low-grade albuminuria and incidence of cardiovascular disease events in nonhypertensive and nondiabetic individuals: the Framingham Heart Study / Circulati
Bakris GL / 2014 / Microalbuminuria as a risk predictor in diabetes:the continuing saga / Diabetes Care 37 : 867 ~ 875
Bidulescu A / 2013 / Gender differences in the association of visceral and subcutaneous adiposity with adiponectin in African Americans: the Jackson Heart Study / BMC Cardio
Eknoyan G / 2003 / Proteinuria and other markers of chronic kidney disease: a position statement of the national kidney foundation (NKF) and the national institute of diabete
Arnlov J / 2005 / Low-grade albuminuria and incidence of cardiovascular disease events in nonhypertensive and nondiabetic individuals: the Framingham Heart Study / Circulati
Bakris GL / 2014 / Microalbuminuria as a risk predictor in diabetes:the continuing saga / Diabetes Care 37 : 867 ~ 875
Bidulescu A / 2013 / Gender differences in the association of visceral and subcutaneous adiposity with adiponectin in African Americans: the Jackson Heart Study / BMC Cardio
Eknoyan G / 2003 / Proteinuria and other markers of chronic kidney disease: a position statement of the national kidney foundation (NKF) and the national institute of diabete
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