지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 364 - 369 (6page)
이용수
초록· 키워드
오류제보하기
Safflower (Carthamus tinctorius) seeds are wellknown traditional oriental medicines that have long been used for the remedies of blood stasis and bone formation in east Asia. In this study, ethyl acetate (EtOAc) was used for extraction of the main chemical compounds from C. tinctorius seeds. Four major compounds were identified, acacetin, cosmosiin, N-feruloyl serotonin and N-(p-coumaroyl) serotonin.
Each compound was evaluated for its inhibitory activity against the inflammatory process of macrophages. All compounds significantly inhibited production of lipopolysaccharide (LPS)- stimulated nitric oxide (NO) and pro-inflammatory cytokines.
The protein levels of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) were dramatically decreased by serotonins in a dose-dependent manner in LPS-stimulated RAW 264.7 macrophages. These results suggest that serotonin derivatives from safflower seeds may reduce inflammationrelated diseases.
목차
등록된 정보가 없습니다.
참고문헌 (23)
참고문헌 신청
Abdelrahman M / 2005 / Beneficial effects of PPAR-(ligands in ischemia-reperfusion injury, inflammation and shock / Cardiovasc Res 65 : 772 ~ 781
Delgado AV / 2003 / Production of tumor necrosis factor-alpha, interleukin 1-beta, interleukin 2, and interleukin 6 by rat leukocyte subpopulations after exposure to substanc
Feldman JM / 1985 / Serotonin content of foods: effect on urinary excretion of 5-hydroxyindoleacetic acid / Am J Clin Nutr 42 : 639 ~ 643
Han SY / 2009 / Protective effects of purified safflower extract on Myocardial ischemia in vivo and in vitro / Phytomedicine 16 : 694 ~ 702
Hewett JA / 1993 / Hepatic and extra hepatic pathobiology of bacterial lipopolysaccharides / Pharmacol Rev 45 : 382 ~ 411
Delgado AV / 2003 / Production of tumor necrosis factor-alpha, interleukin 1-beta, interleukin 2, and interleukin 6 by rat leukocyte subpopulations after exposure to substanc
Feldman JM / 1985 / Serotonin content of foods: effect on urinary excretion of 5-hydroxyindoleacetic acid / Am J Clin Nutr 42 : 639 ~ 643
Han SY / 2009 / Protective effects of purified safflower extract on Myocardial ischemia in vivo and in vitro / Phytomedicine 16 : 694 ~ 702
Hewett JA / 1993 / Hepatic and extra hepatic pathobiology of bacterial lipopolysaccharides / Pharmacol Rev 45 : 382 ~ 411
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Anti-inflammatory Activity of Platycodonis Radix Seed Ethanol Extract in LPS-stimulated Raw 264.7 Macrophages
한국식품영양과학회 학술대회발표집
2016 .10
-
Inhibitory Effects of Safflower Seed Extract on Memory Impairment and Oxidative Stress and the Qualitative Analyses of Serotonin and Its Derivatives in the Water Extracts
한국약용작물학회 학술대회논문집
2018 .05
-
Responses of infammationsignaling pathway by Pyrrosia lingua extracts on pro-infammatoryresponses in LPS-stimulated Raw 264.7 cell
한국식품영양과학회 학술대회발표집
2021 .10
-
Leaves of Raphanus sativus L. Shows Anti-Inflammatory Activity in LPS-Stimulated Macrophages via Suppression of COX-2 and iNOS Expression
Preventive Nutrition and Food Science
2017 .03
-
Anti-inflammatory effects of the aged garlic extracts in LPS-stimulated RAW264.7 cells
한국식품영양과학회 학술대회발표집
2022 .10
-
The 70% EtOH extracts of soft corals collected from Jeju Island have Anti-inflammatory activities in LPS-stimulated RAW 264.7 macrophages
한국수산과학회 양식분과 학술대회
2018 .05
-
Anti-Inflammatory and Antioxidant Action of N-Arachidonoyl Serotonin in RAW264.7 Cells
한국식품영양과학회 학술대회발표집
2015 .08
-
Anti-inflammatory effects of Rosa rugosa seed extract on LPS-stimulated RAW 264.7 cells
한국식품영양과학회 학술대회발표집
2019 .10
-
Anti-inflammatory Effects of Ginseng Seeds Extract on Lipopolysaccharide-stimulated BV2 cells via Downregulation of MAPK Activation
한국식품영양과학회 학술대회발표집
2021 .10
-
Anti-inflammatory effect of ethanol extract of Turbo cornutus in LPS-stimulated RAW 264.7 macrophages and zebrafish model
한국식품영양과학회 학술대회발표집
2020 .10
-
Screening of Vietnamese Medicinal Plants for Anti-Inflammatory Properties in LPS-Induced RAW264.7 Macrophages
한국식품영양과학회 학술대회발표집
2024 .10
-
Anti-Inflammatory Effects of Black Ginseng Extract on RAW264.7 Macrophage Cells Stimulated with LPS
한국식품영양과학회 학술대회발표집
2020 .10
-
Anti-inflammatory Activity of Agrimonia pilosa Ledeb. Extract in LPS-stimulated RAW264.7 Macrophages
한국식품영양과학회 학술대회발표집
2020 .10
-
Anti-Inflammatory Effects of Defatted Hempseed Extract in LPS-stimulated RAW264.7 macrophages and C6 glial cells
한국식품영양과학회 학술대회발표집
2024 .10
-
Ginsenoside Rf suppressed LPS-induced inflammatory mediators in RAW264.7 macrophages
한국식품영양과학회 학술대회발표집
2016 .10
-
Attenuation of lipopolysaccharide-induced inflammatory and oxidative reaction by 5-aminolevulinic acid in RAW 264.7 macrophages and zebrafish larvae
한국수산과학회 양식분과 학술대회
2021 .04
-
ANTI-INFLAMMATORY ACTIVITY OF FERMENTED MARINE BROWN ALGAE EXTRACTS WITH Lactobacillus SP. SH-1 IN LPS-STIMULATED RAW 264.7 MACROPHAGE
한국수산과학회 양식분과 학술대회
2015 .05
-
Anti-inflammatory effect of metabolite A derived from plants in LPS-stimulated Raw264.7 cells
한국식품영양과학회 학술대회발표집
2021 .10
-
Lipopolysaccharide로 유도된 RAW 264.7 세포에서 유색미 에탄올 추출물의 항염증 작용
한국식품영양과학회지
2018 .09
이 논문의 저자 정보
최근 본 자료
댓글(0)
0