지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 116 - 121 (6page)
이용수
초록· 키워드
오류제보하기
Although proteomic analyses have revealed the presence of mitochondrial oxidative phosphorylation (OXPHOS) proteins in the plasma membrane, there have been no in-depth evaluations of the presence or function of OXPHOS I-V in the plasma membrane. Here, we demonstrate the in situ localization of OXPHOS I-V complexes to the sarcolemma of skeletal muscle by immunofluorescence and immunohistochemistry. A portion of the OXPHOS I-V complex proteins was not co-stained with MitoTracker but co-localized with caveolin-3 in the sarcolemma of mouse gastrocnemius. Mitochondrial matrix-facing OXPHOS complex subunits were ectopically expressed in the sarcolemma of the non-permeabilized muscle fibers and C2C12 myotubes. The sarcolemmal localization of cytochrome c was also observed from mouse gastrocnemius muscles and C2C12 myotubes, as determined by confocal and total internal resonance fluorescence (TIRF) microscopy. Based on these data, we conclude that a portion of OXPHOS complexes is localized in the sarcolemma of skeletal muscle and may have non-canonical functions.
목차
등록된 정보가 없습니다.
참고문헌 (35)
참고문헌 신청
Nunnari J / 2012 / Mitochondria : in sickness, in health / Cell 148:1145~1159
Liu X / 1996 / Induction of apoptotic program in cell-free extracts: requirement for dATP, cytochrome c / Cell 86:147~157
Brown DA / 1992 / Sorting of GPI-anchored proteins to glycolipid-enriched membrane subdomains during transport to the apical cell surface / Cell 68:533~544
Munro S / 2003 / Lipid rafts: elusive or illusive? / Cell 115:377~388
Kim KB / 2004 / Two-dimensional electrophoretic analysis reveals that lipid rafts are intact at physiological temperature / Proteomics 4:3527~3535
Liu X / 1996 / Induction of apoptotic program in cell-free extracts: requirement for dATP, cytochrome c / Cell 86:147~157
Brown DA / 1992 / Sorting of GPI-anchored proteins to glycolipid-enriched membrane subdomains during transport to the apical cell surface / Cell 68:533~544
Munro S / 2003 / Lipid rafts: elusive or illusive? / Cell 115:377~388
Kim KB / 2004 / Two-dimensional electrophoretic analysis reveals that lipid rafts are intact at physiological temperature / Proteomics 4:3527~3535
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Compensatory Effect of Mitochondrial OXPHOS in Persistent Organic Pollutants(POPs) on Liver of Mouse
한국생물공학회 학술대회
2019 .10
-
Techniques for investigating mitochondrial gene expression
BMB Reports
2020 .01
-
Pituitary P62 deficiency leads to female infertility by impairing luteinizing hormone production
Experimental and Molecular Medicine
2021 .08
-
The maintenance ability and Ca2+ availability of skeletal muscle are enhanced by sildenafil
Experimental and Molecular Medicine
2016 .01
-
Age-dependent loss of Crls1 causes myopathy and skeletal muscle regeneration failure
Experimental and Molecular Medicine
2024 .04
-
골격근 손상 및 재생 환경에서의 근육 세포 군집 이동의 물리적 특성 가시화
한국가시화정보학회지
2022 .07
-
With the greatest care, stromal interaction molecule (STIM) proteins verify what skeletal muscle is doing
BMB Reports
2018 .01
-
Evaluation of the Effect of Medicinal Plant Extracts on Skeletal Muscle Growth and Improving Muscle Strength
한국생물공학회 학술대회
2023 .10
-
Development of in vitro Human Skeletal Muscle Models Using Microfabricated Devices
한국생물공학회 학술대회
2021 .04
-
골격근 재생 환경에서의 근육 세포 군집 이동의 물리적 특성 가시화
한국가시화정보학회 학술발표대회 논문집
2022 .05
-
Effects of cisplatin on mitochondrial function and autophagy-related proteins in skeletal muscle of rats
BMB Reports
2021 .11
-
A mitochondrial proteome profile indicative of type 2 diabetes mellitus in skeletal muscles
Experimental and Molecular Medicine
2018 .01
-
Purine Precursor Supplementation Increases Productivity of Antibody-expressing CHO Cells by Elevating Intracellular ATP Level
한국생물공학회 학술대회
2024 .09
-
Etiology of genetic muscle disorders induced by mutations in fast and slow skeletal MyBP-C paralogs
Experimental and Molecular Medicine
2023 .03
-
Development of 2D microfluidic experimental setup for studying recovery of skeletal muscle cells
대한기계학회 춘추학술대회
2018 .04
-
A focus on extracellular Ca2+ entry into skeletal muscle
Experimental and Molecular Medicine
2017 .01
-
대체적 근육 손상 치료를 위한 골격근 구조체의 3차원 세포 프린팅
대한기계학회 춘추학술대회
2018 .04
-
3D Printing-assisted Facile Fabrication and Characterization of Uniaxially Stretchable Bioreactor for Improving Directional Organization of Engineered Skeletal Muscle Fibers
한국정밀공학회 학술발표대회 논문집
2024 .11
-
근육유래 바이오 잉크를 이용한 3D 세포 프린팅 근육 구조체 개발
대한기계학회 춘추학술대회
2016 .04
-
Sarcopenia targeting with autophagy mechanism by exercise
BMB Reports
2019 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0