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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2010.1
- 수록면
- 311 - 318 (8page)
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This review explored the mechanism of breast carcinoma progression by focusing on integrins and receptor tyrosine kinases (or growth factor receptors). While the primary role of integrins was previously thought to be solely as mediators of adhesive interactions between cells and extracellular matrices, it is now believed that integrins also regulate signaling pathways that control cancer cell growth, survival, and invasion. A large body of evidence suggests that the cooperation between integrin and receptor tyrosine kinase signaling regulates certain signaling functions that are important for cancer progression.
Recent developments on the crosstalk between integrins and receptor tyrosine kinases, and its implication in mammary tumor progression, are discussed.
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참고문헌 (26)
참고문헌 신청
[학술지(정기간행물)
Aplin, A. E. / 1999 / Cell adhesion molecules, signal transduction and cell growth / Curr. Opin. Cell Biol. 11 : 737 ~ 744
Aumailley, M. / 2000 / Altered synthesis of laminin 1 and absence of basement membrane component deposition in (beta)1 integrin-deficient embryoid bodies / J. Cell Sci. 113 (
Bertotti, A. / 2006 / Beta4 integrin activates a Shp2-Src signaling pathway that sustains HGF-induced anchorage-independent growth / J. Cell Biol. 175 : 993 ~ 1003
Borges, E. / 2000 / Platelet-derived growth factor receptor beta and vascular endothelial growth factor receptor 2 bind to the beta 3 integrin through its extracellular doma
Aplin, A. E. / 1999 / Cell adhesion molecules, signal transduction and cell growth / Curr. Opin. Cell Biol. 11 : 737 ~ 744
Aumailley, M. / 2000 / Altered synthesis of laminin 1 and absence of basement membrane component deposition in (beta)1 integrin-deficient embryoid bodies / J. Cell Sci. 113 (
Bertotti, A. / 2006 / Beta4 integrin activates a Shp2-Src signaling pathway that sustains HGF-induced anchorage-independent growth / J. Cell Biol. 175 : 993 ~ 1003
Borges, E. / 2000 / Platelet-derived growth factor receptor beta and vascular endothelial growth factor receptor 2 bind to the beta 3 integrin through its extracellular doma
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