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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한소아내분비학회 Annals of Pediatirc Endocrinology & Metabolism Annals of Pediatirc Endocrinology & Metabolism 제21권 제2호
- 발행연도
- 2016.1
- 수록면
- 75 - 80 (6page)
이용수
초록· 키워드
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Purpose: Abdominal obesity is a fundamental factor underlying the development of metabolic syndrome. Because of radiation exposure and cost, computed tomography or dual-energy X-ray absorptiometry to evaluate abdominal adiposity are not appropriate in children. Authors evaluated whether ultrasound results could be an indicator of insulin resistance and nonalcoholic fatty liver disease (NAFLD).
Methods: We enrolled 73 subjects (aged 6–16 years) who were evaluated abdominal adiposity by ultrasound. Subcutaneous fat thickness was defined as the measurement from the skin-fat interface to the linea alba, and visceral fat thickness (VFT) was defined as the thickness from the linea alba to the aorta. Anthropometric and biochemical metabolic parameters were also collected and compared. The subjects who met 2 criteria, radiologic confirmed fatty liver and alanine aminotransferase >40, were diagnosed with NAFLD.
Results: There was a strong positive correlation between VFT and obesity. VFT was highly correlated with the homeostasis model assessment for insulin resistance score (r=0.403, P<0.001). The area under the curve for VFT as a predictor of NAFLD was 0.875 (95% confidence interval [CI], 0.787–0.964). VFT of 34.3 mm was found to be the discriminating cutoff for NAFLD (sensitivity, 84.6%; specificity, 71.2%, respectively).
Conclusion: Ultrasound could be useful in measuring VFT and assessing abdominal adiposity in children. Moreover, increased VFT might be an appropriate prognostic factor for insulin resistance and NAFLD.
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참고문헌 (32)
참고문헌 신청
2000 / Obesity: preventing and managing the global epidemic. Report of a WHO consultation / World Health Organ Tech Rep Ser 894(i-xii):1~253
Kim Y / 2014 / The Korea National Health and Nutrition Examination Survey (KNHANES): current status and challenges. Version 2 / Epidemiol Health 36:e2014002
Hedley AA / 2004 / Prevalence of overweight and obesity among US children, adolescents, and adults, 1999-2002 / JAMA 291:2847~2850
박영신 / 2004 / 23년간 서울 지역 초·중·고등학생의 비만 추이 / Korean Journal of Pediatrics 47(3):247~257
Lakka HM / 2002 / Abdominal obesity is associated with increased risk of acute coronary events in men / Eur Heart J 23:706~713
Kim Y / 2014 / The Korea National Health and Nutrition Examination Survey (KNHANES): current status and challenges. Version 2 / Epidemiol Health 36:e2014002
Hedley AA / 2004 / Prevalence of overweight and obesity among US children, adolescents, and adults, 1999-2002 / JAMA 291:2847~2850
박영신 / 2004 / 23년간 서울 지역 초·중·고등학생의 비만 추이 / Korean Journal of Pediatrics 47(3):247~257
Lakka HM / 2002 / Abdominal obesity is associated with increased risk of acute coronary events in men / Eur Heart J 23:706~713
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