지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
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Objectives: We compared the associations of 3 computed tomography (CT)-based abdominal adiposity indexes with non-alcoholic fatty liver disease (NAFLD) among middle-aged Korean men and women. Methods: The participants were 1366 men and 2480 women community-dwellers aged 30-64 years. Three abdominal adiposity indexes?visceral fat area (VFA), subcutaneous fat area (SFA), and visceral-to-subcutaneous fat ratio (VSR)?were calculated from abdominal CT scans. NAFLD was determined by calculating the Liver Fat Score from comorbidities and blood tests. An NAFLD prediction model that included waist circumference (WC) as a measure of abdominal adiposity was designated as the base model, to which VFA, SFA, and VSR were added in turn. The area under the receiver operating characteristic curve (AUC), integrated discrimination improvement (IDI), and net reclassification improvement (NRI) were calculated to quantify the additional predictive value of VFA, SFA, and VSR relative to WC. Results: VFA and VSR were positively associated with NAFLD in both genders. SFA was not significantly associated with NAFLD in men, but it was negatively associated in women. When VFA, SFA, and VSR were added to the WC-based NAFLD prediction model, the AUC improved by 0.013 (p<0.001), 0.001 (p=0.434), and 0.009 (p=0.007) in men and by 0.044 (p<0.001), 0.017 (p<0.001), and 0.046 (p<0.001) in women, respectively. The IDI and NRI were increased the most by VFA in men and VSR in women. Conclusions: Using CT-based abdominal adiposity indexes
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참고문헌 (30)
참고문헌 신청
Stepanova M / 2013 / Predictors of all-cause mortality and liver-related mortality in patients with non-alcoholic fatty liver disease(NAFLD) / Dig Dis Sci 58(10):3017~3023
Paik JM / 2019 / Mortality related to nonalcoholic fatty liver disease is increasing in the United States / Hepatol Commun 3(11):1459~1471
Jakobsen MU / 2007 / Abdominal obesity and fatty liver / Epidemiol Rev 29(1):77~87
Kim D / 2016 / Body fat distribution and risk of incident and regressed nonalcoholic fatty liver disease / Clin Gastroenterol Hepatol 14(1):132~138
Radmard AR / 2016 / Assessment of abdominal fat distribution in non-alcoholic fatty liver disease by magnetic resonance imaging : a population-based study / Arch Iran Med 19(10):693~699
Paik JM / 2019 / Mortality related to nonalcoholic fatty liver disease is increasing in the United States / Hepatol Commun 3(11):1459~1471
Jakobsen MU / 2007 / Abdominal obesity and fatty liver / Epidemiol Rev 29(1):77~87
Kim D / 2016 / Body fat distribution and risk of incident and regressed nonalcoholic fatty liver disease / Clin Gastroenterol Hepatol 14(1):132~138
Radmard AR / 2016 / Assessment of abdominal fat distribution in non-alcoholic fatty liver disease by magnetic resonance imaging : a population-based study / Arch Iran Med 19(10):693~699
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