지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
Translational research helps translate scientific discoveries from bench to clinic. In this brief review, the results of recent translational stroke research are summarized. It covers following topics: 1) peroxisome proliferator-activated receptor-γ (PPAR-γ) to protect against ischemic cerebral infarction, 2) N-methyl-d-aspartate glutamate (NMDA) receptor-dependent activation of sterol regulatory element binding protein-1 (SREBP-1) in ischemic neuronal injuries, 3) regulatory T cells as cerebroprotective immunomodulators in stroke, 4) cerebral interleukin-17-producing γδT cells in the delayed phase of ischemic brain injury, 5) reduction of endoplasmic reticulum (ER) stress and alleviation of atherosclerosis, 6) platelet dense-granule secretion to play a critical roles in thrombosis and subsequent vascular remodeling, and 7) pericyte contraction induced by oxidative-nitrative stress and noreflow phenomenon in cerebral infarction. (Korean J Stroke 2010;12:13-16)
목차
등록된 정보가 없습니다.
참고문헌 (20)
참고문헌 신청
Aitken A / 2006 / 14-3-3 proteins: a historic overview / Semin Cancer Biol 16 : 162 ~ 172
Chang YC / 2007 / Sre1p, a regulator of oxygen sensing and sterol homeostasis, is required for virulence in Cryptococcus neoformans / Mol Microbiol 64 : 614 ~ 629
Erbay E / 2009 / Reducing endoplasmic reticulum stress through a macrophage lipid chaperone alleviates atherosclerosis / Nat Med 15 : 1383 ~ 1391
Home PD / 2009 / RECORD Study Team. Rosiglitazone evaluated for cardiovascular outcomes in oral agent combination therapy for type 2 diabetes (RECORD): a multicentre, randomi
Hotamisligil GS / 2006 / Inflammation and metabolic disorders / Nature 2006; 444 : 860 ~ 867
Chang YC / 2007 / Sre1p, a regulator of oxygen sensing and sterol homeostasis, is required for virulence in Cryptococcus neoformans / Mol Microbiol 64 : 614 ~ 629
Erbay E / 2009 / Reducing endoplasmic reticulum stress through a macrophage lipid chaperone alleviates atherosclerosis / Nat Med 15 : 1383 ~ 1391
Home PD / 2009 / RECORD Study Team. Rosiglitazone evaluated for cardiovascular outcomes in oral agent combination therapy for type 2 diabetes (RECORD): a multicentre, randomi
Hotamisligil GS / 2006 / Inflammation and metabolic disorders / Nature 2006; 444 : 860 ~ 867
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