지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
Antiplatelet drugs are widely used for prevention and treatment of ischemic stroke and transient ischemic attack. Considering the limited efficacy of antiplatelet drugs, combination of antiplatelet drugs can be used to potentiate antiplatelet effect. Compared to aspirin or clopidogrel alone, the combination of aspirin and clopidogrel increased the risk of bleeding complication without any additional benefit. In patients who had nonvalvular atrial fibrillation and were ineligible for oral anticoagulant, the combination aspirin and clopidogrel was better than aspirin alone though the risk of bleeding increased significantly. In two large clinical studies, the combination of aspirin and extended-release dipyridamole was more effective than aspirin alone without increasing bleeding complication. However the result of comparison to clopidogrel alone was disappointing. The combination of aspirin and cilostazol might be better than aspirin alone in preventing the progression of symptomatic stenosis of intracranial artery. Further studies are needed to investigate the risk and benefit of the combination of antiplatelet drugs in selected group of patients with acute ischemic stroke or large artery atherosclerotic stroke. (Korean J Stroke 2010;12:88-95)
목차
등록된 정보가 없습니다.
참고문헌 (32)
참고문헌 신청
Dengler R / 2010 / EARLY Investigators. Early treatment with aspirin plus extended-release dipyridamole for transient ischaemic attack or ischaemic stroke within 24 h of symptom onset (EARLY trial): a randomised, open-label, blindedendpoint trial / Lancet Neurol 9:159~166
cco RL / 2008 / PRoFESS Study Group. Aspirin and extended-release dipyridamole versus clopidogrel for recurrent stroke / N Engl J Med 359:1238~1251
1987 / The European Stroke Prevention Study (ESPS). Principal end-points. The ESPS Group / Lancet 2:1351~1354
1985 / Persantine Aspirin Trial in cerebral ischemia. Part II: Endpoint results. The American-Canadian Co-Operative Study group / Stroke 16:406~415
Bousser MG / 1983 / “AICLA” controlled trial of aspirin and dipyridamole in the secondary prevention of athero-thrombotic cerebral ischemia / Stroke 14:5~14
cco RL / 2008 / PRoFESS Study Group. Aspirin and extended-release dipyridamole versus clopidogrel for recurrent stroke / N Engl J Med 359:1238~1251
1987 / The European Stroke Prevention Study (ESPS). Principal end-points. The ESPS Group / Lancet 2:1351~1354
1985 / Persantine Aspirin Trial in cerebral ischemia. Part II: Endpoint results. The American-Canadian Co-Operative Study group / Stroke 16:406~415
Bousser MG / 1983 / “AICLA” controlled trial of aspirin and dipyridamole in the secondary prevention of athero-thrombotic cerebral ischemia / Stroke 14:5~14
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
신속혈소판기능검사를 이용한 허혈성 뇌졸중 환자에서 아스피린 저항성의 빈도와 관련인자 - 예비연구
대한뇌졸중학회지
2006 .01
-
Medical Treatment of Intracranial Atherosclerosis: An Update
대한뇌졸중학회지
2017 .01
-
Determination of the Prevalence of Aspirin and Clopidogrel Resistances in Patients with Coronary Artery Disease by using Various Platelet-function Tests
Annals of Laboratory Medicine
2010 .01
-
Dual Antiplatelet Therapy after Noncardioembolic Ischemic Stroke or Transient Ischemic Attack: Pros and Cons
Journal of Clinical Neurology
2014 .01
-
아스피린 저항성: 단순한 검사 소견인가 또는 중요한 임상 기준인가?
대한내과학회지
2009 .01
-
Low-Molecular-Weight Heparin or Dual Antiplatelet Therapy Is More Effective Than Aspirin Alone in Preventing Early Neurological Deterioration and Improving the 6-Month Outcome in Ischemic Stroke Patients
Journal of Clinical Neurology
2015 .01
-
2009년 한국 뇌졸중 진료지침에서 이차예방을 위한 항혈소판제 사용에 관한 내용의 부분 개정
대한뇌졸중학회지
2010 .01
-
Antiplatelet Effect of Low Dose Aspirin: Pharmacokinetic/Pharmacodynamic Analysis
대한임상약리학회 학술대회
1996 .01
-
Risk of Hemorrhage Attributed to Underlying Chronic Diseases and Uninterrupted Aspirin Therapy of Patients Undergoing Minor Oral Surgical Procedures: A Retrospective Cohort Study
예방의학회지
2017 .01
-
허혈성 심장질환 환자에서 스타틴과 병용하는 항혈소판제 종류에 따른 임상결과
한국임상약학회지
2019 .01
-
허혈성 뇌졸중에서의 항혈전 치료
영남의대학술지
2003 .01
-
세 가지 이상의 항혈소판제 약물과민반응 환자에서 성공적인 급속 순차적 탈감작요법 1예
Allergy Asthma & Respiratory Diseases
2016 .01
-
관상동맥 스텐트 삽입술 후 Ultegra rapid platelet function Assay-ASA을 이용한 Aspirin 저항성의 임상적 의의
대한내과학회지
2009 .01
-
한국의 한 대학병원 환자에서의 아스피린 저항성의 빈도
Annals of Laboratory Medicine
2008 .01
-
Continuous Use of Thienopyridine May Be as Safe as Low-Dose Aspirin in Endoscopic Resection of Gastric Tum
Gut and Liver
2018 .01
-
Cilostazol Reduces PAC-1 Expression on Platelets in Ischemic Stroke
Journal of Clinical Neurology
2008 .01
-
A preliminary study: aspirin discontinuation before elective operations; when is the optimal timing?
Annals of Surgical Treatment and Research
2013 .10
-
Long-Term Low-Dose Aspirin Use Reduces Gastric Cancer Incidence: A Nationwide Cohort Study
Cancer Research and Treatment
2016 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0