지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 295 - 302 (8page)
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초록· 키워드
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Background/Aims: The aim of this study was to evaluate the relationship between controlled attenuation parameter (CAP) and hepatic steatosis, as assessed by ultrasound (US) in patients with alcoholic liver disease (ALD) or non-alcoholic fatty liver disease (NAFLD). Methods: Patients with either ALD or NAFLD who were diagnosed with fatty liver with US and whose CAP scores were measured, were retrospectively enrolled in this study. The degree of hepatic steatosis assessed by US was categorized into mild (S1), moderate (S2), and severe (S3). Results: A total of 186 patients were included: 106 with NAFLD and 80 with ALD. Regarding hepatic steatosis, the CAP score was significantly correlated with US (ρ=0.580, p<0.001), and there was no significant difference between the NAFLD and ALD groups (ρ=0.569, p<0.001; ρ=0.519, p<0.001; p=0.635). Using CAP, area under receiver operating characteristic curves for ≥S2 and ≥S3 steatosis were excellent (0.789 and 0.843, respectively). For sensitivity ≥90%, CAP cutoffs for the detection of ≥S2 and ≥S3 steastosis were separated with a gap of approximately 35 dB/m in all patients and in each of the NAFLD and ALD groups. Conclusions: The CAP score is well correlated with hepatic steatosis, as assessed by US, in both ALD and NAFLD.
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참고문헌 (24)
참고문헌 신청
Levene AP / 2012 / The epidemiology, pathogenesis and histopathology of fatty liver disease / Histopathology 61:141~152
Lazo M / 2008 / The epidemiology of nonalcoholic fatty liver disease: a global perspective / Semin Liver Dis 28:339~350
Bellentani S / 2000 / Prevalence of and risk factors for hepatic steatosis in Northern Italy / Ann Intern Med 132:112~117
Cerović I / 2013 / Alcoholic liver disease/nonalcoholic fatty liver disease index: distinguishing alcoholic from nonalcoholic fatty liver disease / Eur J Gastroenterol Hepatol 25:899~904
Myers RP / 2012 / Controlled attenuation parameter (CAP): a noninvasive method for the detection of hepatic steatosis based on transient elastography / Liver Int 32:902~910
Lazo M / 2008 / The epidemiology of nonalcoholic fatty liver disease: a global perspective / Semin Liver Dis 28:339~350
Bellentani S / 2000 / Prevalence of and risk factors for hepatic steatosis in Northern Italy / Ann Intern Med 132:112~117
Cerović I / 2013 / Alcoholic liver disease/nonalcoholic fatty liver disease index: distinguishing alcoholic from nonalcoholic fatty liver disease / Eur J Gastroenterol Hepatol 25:899~904
Myers RP / 2012 / Controlled attenuation parameter (CAP): a noninvasive method for the detection of hepatic steatosis based on transient elastography / Liver Int 32:902~910
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