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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.6
- 수록면
- 385 - 393 (9page)
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초록· 키워드
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Background: The root and rhizome are historically and officially utilized medicinal parts of Panax notoginseng (PN) (Burk.) F. H. Chen, which in raw and steamed forms are used differently in practice.
Methods: To investigate the differences in chemical composition and bioactivities of PN root and rhizome between raw and steamed forms, high-performance liquid chromatography analyses and pharmacologic effects evaluated by tests of anticoagulation, antioxidation, hemostasis, antiinflammation, and hematopoiesis were combined.
Results: With the duration of steaming time, the contents of ginsenosides Rg1, Re, Rb1, Rd, and notoginsenoside R₁ in PN were decreased, while those of ginsenosides Rh₁, 20(S)-Rg3, 20(R)-Rg3, Rh4, and Rk₃ were increased gradually. Raw PN samples steamed for 6 h at 120℃ with stable levels of most constituents were used for the subsequent study of bioeffects. Raw PN showed better hemostasis, anticoagulation, and antiinflammation effects, while steamed PN exhibited stronger antioxidation and hematopoiesis activities. For different parts of PN, contents of saponins in PN rhizome were generally higher than those in the root, which could be related to the stronger bioactivities of rhizome compared with the same form of PN root.
Conclusion: This study provides basic information about the chemical and bioactive comparison of PN root and rhizome in both raw and steamed forms, indicating that the change of saponins may have a key role in different properties of raw and steamed PN.
Methods: To investigate the differences in chemical composition and bioactivities of PN root and rhizome between raw and steamed forms, high-performance liquid chromatography analyses and pharmacologic effects evaluated by tests of anticoagulation, antioxidation, hemostasis, antiinflammation, and hematopoiesis were combined.
Results: With the duration of steaming time, the contents of ginsenosides Rg1, Re, Rb1, Rd, and notoginsenoside R₁ in PN were decreased, while those of ginsenosides Rh₁, 20(S)-Rg3, 20(R)-Rg3, Rh4, and Rk₃ were increased gradually. Raw PN samples steamed for 6 h at 120℃ with stable levels of most constituents were used for the subsequent study of bioeffects. Raw PN showed better hemostasis, anticoagulation, and antiinflammation effects, while steamed PN exhibited stronger antioxidation and hematopoiesis activities. For different parts of PN, contents of saponins in PN rhizome were generally higher than those in the root, which could be related to the stronger bioactivities of rhizome compared with the same form of PN root.
Conclusion: This study provides basic information about the chemical and bioactive comparison of PN root and rhizome in both raw and steamed forms, indicating that the change of saponins may have a key role in different properties of raw and steamed PN.
목차
ABSTRACT
1. Introduction
2. Materials and methods
3. Results and discussion
4. Conclusions
References
참고문헌 (31)
참고문헌 신청
Fang Li / 2017 / Chemical and bioactive comparison of flowers of Panax ginseng Meyer, Panax quinquefolius L., and Panax notoginseng Burk. / Journal of Ginseng Research 41(4):487~495
Chinese pharmacopoeia / 2015 / Notoginseng Radix et Rhizoma, vol. 1
U.S.A Herbal medicines Compendium 1.0 / Notoginseng Radix et Rhizoma
British pharmacopoeia / 2014 / Notoginseng root, vol. IV
European pharmacopoeia 8.0 / Notoginseng root
Chinese pharmacopoeia / 2015 / Notoginseng Radix et Rhizoma, vol. 1
U.S.A Herbal medicines Compendium 1.0 / Notoginseng Radix et Rhizoma
British pharmacopoeia / 2014 / Notoginseng root, vol. IV
European pharmacopoeia 8.0 / Notoginseng root
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