지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.1
- 수록면
- 285 - 291 (7page)
이용수
초록· 키워드
오류제보하기
Background and Purpose We aimed to determine the patterns and mechanisms of persistent nystagmus (PN) lasting >1 year in lateral medullary infarction (LMI). Methods We recruited 13 patients with PN due to LMI and another 13 with transient nystagmus (TN) (<1 year) as control. All patients underwent oculography, rotatory chair test, caloric test, bedside head impulse test, dizziness handicap inventory (DHI), and brain MRI. Results All patients had spontaneous, contralesional, horizontal-torsional nystagmus during the acute phase. Although two patients exhibited consistent contralesional torsional nystagmus, most patients (11/13, 85%) with PN evolved from the initial contralesional to ipsilesional nystagmus. During horizontal gaze, the patterns of ipsilesional PN were diverse; torsional (n=5), torsional-downbeat (n=2), horizontal (n=2), and horizontal nystagmus while looking at the lesion side, and torsional nystagmus while looking at the opposite side (n=2). During rotatory chair test, the gains of the vestibulo-ocular reflex in the PN group were lower than those in the TN group to the lesion side at 0.02 and 0.64 Hz. The caudal and ventrolateral parts of the vestibular nuclei were mostly involved in patients with PN. The DHI score did not differ between the groups. Conclusions PN patterns frequently change in LMI. Resultant vestibular asymmetry after vestibular afferents or cerebellar inhibitory pathway damage and/or inappropriate vestibular compensation may be responsible for PN in LMI. Impairment of the horizontal or vertical neural integrators may be another cause. The presence of PN does not necessarily indicate more severe dizziness in LMI.
목차
등록된 정보가 없습니다.
참고문헌 (20)
참고문헌 신청
Brazis PW / 1992 / Ocular motor abnormalities in Wallenberg’s lateral medullary syndrome / Mayo Clin Proc 67:365~368
Rambold H / 2005 / Spontaneous nystagmus in dorsolateral medullary infarction indicates vestibular semicircular canal imbalance / J Neurol Neurosurg Psychiatry 76:88~94
Dieterich M / 1992 / Wallenberg’s syndrome : lateropulsion, cyclorotation, and subjective visual vertical in thirty-six patients / Ann Neurol 31:399~408
성기범 / 2009 / 동측안진을 보인 원발성 연수출혈에 의한 외측연수증후군 1예 / Research in Vestibular Science 8(1):52~55
Uemura T / 1973 / Effects of vestibular nuclei lesions on vestibuloocular reflexes and posture in monkeys / Acta Otolaryngol Suppl 315:1~71
Rambold H / 2005 / Spontaneous nystagmus in dorsolateral medullary infarction indicates vestibular semicircular canal imbalance / J Neurol Neurosurg Psychiatry 76:88~94
Dieterich M / 1992 / Wallenberg’s syndrome : lateropulsion, cyclorotation, and subjective visual vertical in thirty-six patients / Ann Neurol 31:399~408
성기범 / 2009 / 동측안진을 보인 원발성 연수출혈에 의한 외측연수증후군 1예 / Research in Vestibular Science 8(1):52~55
Uemura T / 1973 / Effects of vestibular nuclei lesions on vestibuloocular reflexes and posture in monkeys / Acta Otolaryngol Suppl 315:1~71
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