지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.12
- 수록면
- 83 - 88 (6page)
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초록· 키워드
오류제보하기
Purpose: Double primary colorectal cancer (CRC) and gastric cancer (GC) represent the most common multiple primary malignant tumors (MPMT) in Korea. The recognition and screening of hidden malignancies other than the primary cancer are critical. This study aimed to investigate the clinicopathologic characteristics and survival rates in patients with synchronous or metachronous double primary CRC and GC.
Methods: Between January 1994 and May 2018, 11,050 patients were diagnosed with CRC (n=5,454) or GC (n=5,596) at Gil Medical Center. MPMT and metastatic malignant tumors were excluded from this study. A total of 103 patients with double primary CRC and GC were divided into two groups: the synchronous group (n=40) and the metachronous group (n=63). The incidence, clinicopathologic characteristics, and survival rate of the two groups were analyzed.
Results: The incidence of synchronous and metachronous double primary CRC and GC was 0.93%. Double primary CRC and GC commonly occurred in male patients aged over 60 years with low comorbidities and minimal previous cancer history. There were significant differences between the synchronous and metachronous groups in terms of age, morbidity, and overall survival. Metachronous group patients were 6 years younger on average (P=0.009), had low comorbidities (P=0.008), and showed a higher 5-year overall survival rate (94.8% and 61.3%, P<0.001) in contrast to synchronous group.
Conclusion: When primary cancer (CRC or GC) is detected, it is important to be aware of the possibility of the second primary cancer (GC or CRC) development at that time or during follow-up to achieve early detection and better prognosis.
Methods: Between January 1994 and May 2018, 11,050 patients were diagnosed with CRC (n=5,454) or GC (n=5,596) at Gil Medical Center. MPMT and metastatic malignant tumors were excluded from this study. A total of 103 patients with double primary CRC and GC were divided into two groups: the synchronous group (n=40) and the metachronous group (n=63). The incidence, clinicopathologic characteristics, and survival rate of the two groups were analyzed.
Results: The incidence of synchronous and metachronous double primary CRC and GC was 0.93%. Double primary CRC and GC commonly occurred in male patients aged over 60 years with low comorbidities and minimal previous cancer history. There were significant differences between the synchronous and metachronous groups in terms of age, morbidity, and overall survival. Metachronous group patients were 6 years younger on average (P=0.009), had low comorbidities (P=0.008), and showed a higher 5-year overall survival rate (94.8% and 61.3%, P<0.001) in contrast to synchronous group.
Conclusion: When primary cancer (CRC or GC) is detected, it is important to be aware of the possibility of the second primary cancer (GC or CRC) development at that time or during follow-up to achieve early detection and better prognosis.
목차
INTRODUCTION
METHODS
RESULTS
DISCUSSION
REFERENCES
참고문헌 (25)
참고문헌 신청
[학술지(정기간행물)] - Watson TA / 1953 / Incidence of multiple cancer / Cancer 6 : 365 ~ 371
[학술지(정기간행물)] - 하태경 / 2007 / Surgical Outcome of Synchronous Second Primary Cancer in Patients with Gastric Cancer / Yonsei Medical Journal 48 (6) : 981 ~ 987
[학술지(정기간행물)] - Moertel CG / 1977 / Multiple primary malignant neoplasms: historical perspectives / Cancer 40 (4 Suppl) : 1786 ~ 1792
[학술지(정기간행물)] - Watanabe S / 1984 / Multiple primary cancers in 5,456 autopsy cases in the National Cancer Center of Japan / J Natl Cancer Inst 72 : 1021 ~ 1027
[학술지(정기간행물)] - Ja Seong Bae / 2006 / Characteristics of Synchronous Cancers in Gastric Cancer Patients / Cancer Research and Treatment 38 (1) : 25 ~ 29
[학술지(정기간행물)] - 하태경 / 2007 / Surgical Outcome of Synchronous Second Primary Cancer in Patients with Gastric Cancer / Yonsei Medical Journal 48 (6) : 981 ~ 987
[학술지(정기간행물)] - Moertel CG / 1977 / Multiple primary malignant neoplasms: historical perspectives / Cancer 40 (4 Suppl) : 1786 ~ 1792
[학술지(정기간행물)] - Watanabe S / 1984 / Multiple primary cancers in 5,456 autopsy cases in the National Cancer Center of Japan / J Natl Cancer Inst 72 : 1021 ~ 1027
[학술지(정기간행물)] - Ja Seong Bae / 2006 / Characteristics of Synchronous Cancers in Gastric Cancer Patients / Cancer Research and Treatment 38 (1) : 25 ~ 29
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UCI(KEPA) : I410-ECN-0101-2019-514-000326852