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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 충남대학교 농업과학연구소 Korean Journal of Agricultural Science Korean Journal of Agricultural Science Vol.45 No.2
- 발행연도
- 2018.6
- 수록면
- 238 - 247 (10page)
이용수
초록· 키워드
오류제보하기
The overall consumption of meat is increasing as the level of national income increases. The end weight is a trait closely associated with dressed meat. Genome-wide association study (GWAS) is an effective method of analyzing genetic variation and gene identification associated with a number of natural alternative traits because it can detect variations. So this paper did a GWAS analysis to identity the location on the genome related to the end weight in purebred landrace pigs and to explore the relevant candidate gene. This study identified a significant single nucleotide poly morphism (SNP) marker in chromosome 6 (ASGA0029422, p = 1.22 ｘ 10<SUP>-6</SUP>). Adhesion G protein-coupled receptor L2 (ADGRL2 ) was found to be the candidate gene at the identified SNP marker location. ADGRL2 genes have been found to be associated with cell development in relation to the external and internal environment of a cell. In addition, genotype and statistical analyses were done on nine variations on the exon of ADGRL2 . The results show that the SNP marker (ASGA0029422, p = 1.32 × 10<SUP>-6</SUP>) was significant, but the significance of the nine variations on the ADGRL2 exon was not verified. However, by performing further experiments and functional studies on other SNPs showing possible genetic ADGRL-Exon mutations, objects with high associations of high-end weights can be selected.
목차
Abstract
Introduction
Materials and Methods
Results and Discussion
References
참고문헌 (36)
참고문헌 신청
[학술지(정기간행물)] - Barrett JC / 2005 / Haploview: Analysis and visualization of LD and haplotype maps / Bioinformatics 21 : 263 ~ 265
[단행본] - Birren B / 1997 / Genome analysis: A laboratory manual / Cold Spring Harbor Laboratory Press : 14 ~
[학술지(정기간행물)] - Borowska A / 2017 / Detection of pig genome regions determining production traits using an information theory approach / Livestock Science 205 : 31 ~ 35
[학술지(정기간행물)] - Bruininx EM / 2001 / Individually measured feed intake characteristics and growth performance of group-housed weanling pigs: Effects of sex, initial body weight, and body weight distribution within groups / Journal of Animal Science 79 : 301 ~ 308
[학술지(정기간행물)] - Carney EE / 2009 / Effect of dam parity on growth performance and immunity of weaned pigs / Nebraska Swine Reports 233 : 29 ~ 32
[단행본] - Birren B / 1997 / Genome analysis: A laboratory manual / Cold Spring Harbor Laboratory Press : 14 ~
[학술지(정기간행물)] - Borowska A / 2017 / Detection of pig genome regions determining production traits using an information theory approach / Livestock Science 205 : 31 ~ 35
[학술지(정기간행물)] - Bruininx EM / 2001 / Individually measured feed intake characteristics and growth performance of group-housed weanling pigs: Effects of sex, initial body weight, and body weight distribution within groups / Journal of Animal Science 79 : 301 ~ 308
[학술지(정기간행물)] - Carney EE / 2009 / Effect of dam parity on growth performance and immunity of weaned pigs / Nebraska Swine Reports 233 : 29 ~ 32
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UCI(KEPA) : I410-ECN-0101-2018-520-003133115