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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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Objectives: This study was performed to investigate anti-obesity effects of Zingiberis Rhizoma on ovariectomized rats in order to determine the possibility of the clinical use in preventing and treating post-menopausal obesity.
Methods: To investigate how menopause affects obesity in woman, rats were treated with Zingiberis Rhizoma extracts. We measured various biomarkers including GOT,GPT, leptin, ghrelin, adiponectin, PPAR-γ mRNA, total cholesterol, triglyceride, HDL-cholesterol, liver weight, estradiol, uterine weight, and calcitonin, which are linked with obesity and menopause.
Results: There was a significant decrease in group which was given Zingiberis Rhizoma extracts 100 mg/kg and lipid level found in blood(total cholesterol, triglyceride). Fat accumulation of liver cells was repressed, liver function was improved and leptin and adipomectin levels were significantly normalized. In addition, expression of PPAR-γ was significantly increased.
Conclusions: The results indicated that Zingiberis Rhizoma extracts have anti-obesity effects on ovariectomized rats through improving liver function and lipid metabolic function.
Methods: To investigate how menopause affects obesity in woman, rats were treated with Zingiberis Rhizoma extracts. We measured various biomarkers including GOT,GPT, leptin, ghrelin, adiponectin, PPAR-γ mRNA, total cholesterol, triglyceride, HDL-cholesterol, liver weight, estradiol, uterine weight, and calcitonin, which are linked with obesity and menopause.
Results: There was a significant decrease in group which was given Zingiberis Rhizoma extracts 100 mg/kg and lipid level found in blood(total cholesterol, triglyceride). Fat accumulation of liver cells was repressed, liver function was improved and leptin and adipomectin levels were significantly normalized. In addition, expression of PPAR-γ was significantly increased.
Conclusions: The results indicated that Zingiberis Rhizoma extracts have anti-obesity effects on ovariectomized rats through improving liver function and lipid metabolic function.
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참고문헌
참고문헌 (37)
참고문헌 신청
[단행본] - The society of korean medicine obstetrics and gynecology / 2016 / Oreiental obstetrcis & gynecology / Euiseongdang publishing company : 228 ~ 229
[단행본] - Choi YD / 2001 / Clinical gynecology / Koera medical book publishing company : 305 ~ 326
[학술지(정기간행물)] - Carr MC / 2003 / The emergence of the metabolic syndrome with menopause / J CLin Endocrinol Metab 88 : 2404 ~ 2411
[학술지(정기간행물)] - Ozebey N / 2002 / Body fat distribution and cardiobascular disease risk factors in pre and post menopausal obese women with similar BMI / Endocr J 49 (4) : 503 ~ 509
[학술지(정기간행물)] - 김수지 / 2016 / 당귀(Angelica gigas N.)와 토사자(Cuscuta chinensis Lam.)를 포함하는 생약 복합 추출물의 폐경 동물모델에서의 갱년기 증상 완화 효과 / 한국식품영양과학회지 45 (8) : 1083 ~ 1089
[단행본] - Choi YD / 2001 / Clinical gynecology / Koera medical book publishing company : 305 ~ 326
[학술지(정기간행물)] - Carr MC / 2003 / The emergence of the metabolic syndrome with menopause / J CLin Endocrinol Metab 88 : 2404 ~ 2411
[학술지(정기간행물)] - Ozebey N / 2002 / Body fat distribution and cardiobascular disease risk factors in pre and post menopausal obese women with similar BMI / Endocr J 49 (4) : 503 ~ 509
[학술지(정기간행물)] - 김수지 / 2016 / 당귀(Angelica gigas N.)와 토사자(Cuscuta chinensis Lam.)를 포함하는 생약 복합 추출물의 폐경 동물모델에서의 갱년기 증상 완화 효과 / 한국식품영양과학회지 45 (8) : 1083 ~ 1089
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