지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.4
- 수록면
- 160 - 165 (6page)
이용수
초록· 키워드
오류제보하기
BACKGROUND/OBJECTIVES: Korea is quickly becoming an aged society. Dementia is also becoming a vital public health problem in Korea. Cognitive impairment as a pre-stage of dementia shares most risk factors for dementia. The aim of the present study was to determine associations of serum levels of vitamins A, C, and E with the risk of cognitive impairment among elderly Koreans.
SUBJECTS/METHODS: In this cross-sectional study, a total of 230 participants aged 60-79 years from Yangpyeong cohort were included. Cognitive function was assessed by the Korean version of the Mini-Mental State Examination for Dementia Screening. The logistic multivariable regression model was applied to determine the effect of serum vitamins A, C, and E on the risk of cognitive impairment.
RESULTS: There was no significant association between the risk of cognitive impairment and serum levels of vitamin A and vitamin C. There was a significant odd ratio when the second tertile group of beta-gamma tocopherol level was compared to the first tertile group [odds ratio (OR) = 0.37, 95% confidence interval (CI) = 0.14-0.98, P for trend = 0.051]. In subgroup analyses, there were significant negative associations between beta-gamma tocopherol level and the risk of cognitive impairment in men (OR = 0.17, 95% CI = 0.03-0.87, P for trend = 0.028), non-drinkers or former drinkers (OR = 0.13, 95% CI = 0.02-0.66, P for trend = 0.025), and non-smokers or former smokers (OR = 0.27, 95% CI = 0.09-0.82, P for trend = 0.017).
CONCLUSION: Serum beta-gamma tocopherol levels tended to be inversely associated with the risk of cognitive impairment. Further prospective large-scaled studies are needed to examine this association.
SUBJECTS/METHODS: In this cross-sectional study, a total of 230 participants aged 60-79 years from Yangpyeong cohort were included. Cognitive function was assessed by the Korean version of the Mini-Mental State Examination for Dementia Screening. The logistic multivariable regression model was applied to determine the effect of serum vitamins A, C, and E on the risk of cognitive impairment.
RESULTS: There was no significant association between the risk of cognitive impairment and serum levels of vitamin A and vitamin C. There was a significant odd ratio when the second tertile group of beta-gamma tocopherol level was compared to the first tertile group [odds ratio (OR) = 0.37, 95% confidence interval (CI) = 0.14-0.98, P for trend = 0.051]. In subgroup analyses, there were significant negative associations between beta-gamma tocopherol level and the risk of cognitive impairment in men (OR = 0.17, 95% CI = 0.03-0.87, P for trend = 0.028), non-drinkers or former drinkers (OR = 0.13, 95% CI = 0.02-0.66, P for trend = 0.025), and non-smokers or former smokers (OR = 0.27, 95% CI = 0.09-0.82, P for trend = 0.017).
CONCLUSION: Serum beta-gamma tocopherol levels tended to be inversely associated with the risk of cognitive impairment. Further prospective large-scaled studies are needed to examine this association.
목차
INTRODUCTION
SUBJECTS AND METHODS
RESULTS
DISCUSSION
REFRENCES
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Associations of serum levels of vitamins A, C, and E with the risk of cognitive impairment among elderly Koreans
Nutrition Research and Practice
2018 .04
-
Up-regulation of miR-106a targets LIMK1 and contributes to cognitive impairment induced by isoflurane anesthesia in mice
Genes & Genomics
2020 .01
-
한국 성인의 항산화 비타민 섭취와 대사증후군 위험 간의 관련성
Journal of Nutrition and Health
2017 .08
-
The Association of Serum Vitamin D With Anthropometric Indices, Lipid Profile, ICAM-1, and IL-17 in Patients Undergoing Coronary Artery Bypass Graft Surgery
Clinical Nutrition Research
2024 .07
-
Vitamin E status of 20- to 59-year-old adults living in the Seoul metropolitan area of South Korea
Nutrition Research and Practice
2015 .04
-
Vitamin E status of 20- to 59-year-old adults living in the Seoul metropolitan area of South Korea
Nutrition Research and Practice
2015 .04
-
Serum vitamin D status and metabolic syndrome: a systematic review and dose-response meta-analysis
Nutrition Research and Practice
2021 .06
-
Serum vitamin D status and metabolic syndrome: a systematic review and dose-response meta-analysis
Nutrition Research and Practice
2021 .06
-
Evidence and suggestions for establishing vitamin D intake standards in Koreans for the prevention of chronic diseases
Nutrition Research and Practice
2022 .05
-
Evidence and suggestions for establishing vitamin D intake standards in Koreans for the prevention of chronic diseases
Nutrition Research and Practice
2022 .05
-
제5기 국민건강영양조사 자료 중 성인 남성에서 비타민 D와 고밀도 지단백 콜레스테롤의 관련성
Korean Journal of Health Promotion
2019 .01
-
Efficacy and Safety of Intramuscular Injections of Vitamin D3 B.O.N. on Serum Vitamin D Levels in Adults with Vitamin D Deficiency: A Prospective, Single-Center, Open-Label Study
Korean Journal of Health Promotion
2024 .03
-
한국 성인의 비타민 E 섭취량 및 급원식품군의 현황 및 추이 : 제 1~6기 국민건강 영양조사 자료를 이용하여
Journal of Nutrition and Health
2017 .10
-
경남 일부지역 중학생의 비타민 D 영양상태 및 관련 요인에 관한 연구
동아시아식생활학회지
2019 .10
-
The Difference between Serum Vitamin D Level and Depressive Symptoms in Korean Adult Women before and after Menopause: The 5th (2010–2012) Korean National Health and Nutrition Examination Survey
Korean Journal of Health Promotion
2023 .03
-
The Relationship between Serum Vitamin C and Uric Acid Levels, Antioxidant Status and Coronary Artery Disease: a Case-Control Study
Clinical Nutrition Research
2020 .01
-
The Association between Dietary Vitamin A and C Intakes and Cataract: Data from Korea National Health and Nutrition Examination Survey 2012
Clinical Nutrition Research
2020 .01
-
The factors associated with Vitamin D deficiency in community dwelling elderly in Korea
Nutrition Research and Practice
2018 .10
-
The factors associated with Vitamin D deficiency in community dwelling elderly in Korea
Nutrition Research and Practice
2018 .10
-
시판 가공식품의 비타민 A, E 함량 조사 연구 - 음료수, 시리얼, 과자, 기타코코아·당류·초콜릿가공품 등을 중심으로 -
한국식품조리과학회지
2016 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0
UCI(KEPA) : I410-ECN-0101-2018-594-001904692