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학제간연구 과학기술학 뇌인지과학 기술정책 기타 복합학

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논문 기본 정보

자료유형
학술저널
저자정보
Sang-Yong Park (Kyung Hee University) Yu-Kyong Shin (Kyung Hee University) Hee-Taek Kim (Semyung University) Yong Min Kim (Semyung University) Don-Gil Lee (Kyung Hee University) Eunson Hwang (Kyung Hee University) Byung-Goo Cho (Korea Ginseng) Chang Shik Yin (Kyung Hee University) Ki-Young Kim (Kyung Hee University) Tae Hoo Yi (Kyung Hee University)
저널정보
고려인삼학회 Journal of Ginseng Research Journal of Ginseng Research Vol.40 No.3
발행연도
2016.7
수록면
260 - 268 (9page)

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초록· 키워드

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Background: During the aging process, skin shows visible changes, characterized by a loss of elasticity and the appearance of wrinkles due to reduced collagen production and decreased elasticity of elastin fibers. Panax ginseng Meyer has been used as a traditional medicine for various diseases due to its wide range of biological activities including skin protective effects. Ginsenosides are the main components responsible for the biological activities of ginseng. However, the protective activities of an enzymatic preparation of red ginseng against human skin aging have not been investigated.
Methods: The efficacy of an enzyme-treated powder complex of red ginseng (BG11001) in preventing human skin aging was evaluated by oral administration to 78 randomized individuals. All patients were requested to take three daily capsules containing either 750 mg of BG11001 or a placebo vehicle for 24 wk; at the end of the testing period, skin roughness, elasticity, and skin water content were measured.
Results: BG11001 significantly reduced the average roughness of eye wrinkles and the Global Photo Damage Score compared with the placebo, although there were no significant differences in arithmetic roughness average between the groups. In addition, gross elasticity and net elasticity values increased, and transepidermal water loss level decreased, indicating improved skin elasticity and moisture content.
Conclusion: In conclusion, enzyme-treated red ginseng extract significantly improved eye wrinkle roughness, skin elasticity, and moisture content. Moreover, enzyme-treated red ginseng extract would be useful substance as a bio-health skin care product.
#elasticity #enzyme-treated red ginseng #human skin #Panax ginseng #wrinkle

목차

ABSTRACT
1. Introduction
2. Materials and methods
3. Results
4. Discussion
References

참고문헌 (31)

참고문헌 신청
[학술지(정기간행물)] - Farage MA / 2013 / Characteristics of the aging skin / Adv Wound Care (New Rochelle) 2 : 5 ~ 10 google schola [학술지(정기간행물)] - Proksch E / 2014 / Oral intake of specific bioactive collagen peptides reduces skin wrinkles and increases dermal matrix synthesis / Skin Pharm Physiol 27 : 113 ~ 119 google schola [학술지(정기간행물)] - Takema Y / 1994 / Age-related changes in the elastic properties and thickness of human facial skin / Br J Dermatol 131 : 641 ~ 648 google schola [학술지(정기간행물)] - Takema Y / 1995 / The relationship between age-related changes in the physical properties and development of wrinkles in human facial skin / J Soc Cosmet Chem 46 : 163 ~ 173 google schola [학술지(정기간행물)] - 홍창의 / 2011 / Anti-inflammatory and Anti-oxidative Effects of Korean Red Ginseng Extract in Human Keratinocytes / Immune Network 11 (1) : 42 ~ 49 google schola

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