메뉴 건너뛰기
Library Notice
Institutional Access
If you certify, you can access the articles for free.
Check out your institutions.
ex)Hankuk University, Nuri Motors
Log in Register Help KOR
Subject
Humanities
General Humanities History Philosophy Religious Studies Linguistics and Literature Other Humanities
Social science
General Social Science Business Management Tourism Education Military Science Library and Information Science Law Sociology Journalism and Media Studies Psychological Science Political Science and Diplomacy Geography Public Administration Economics International Trade Anthropology Other Social Science
Natural science
General Natural Science Physics Biology Life Sciences Mathematics/Statistics Astronomy Earth Science Chemistry Other Natural Science
Engineering
General Engineering Architectural Engineering Mechanical Engineering Industrial Engineering Material/Energy Engineering Electrical and Electronic Engineering Marine and Ocean Engineering Chemical Engineering Computer Science Other Engineering
Medical science
General Medical Science Nursing Science Veterinary Pharmacy Traditional Korean Medicine Basic Medicine Clinical Medicine Other Medicine
Agriculture and Fishery
General Agriculture and Fishery Agriculture Fishery Science Food Science Forestry Animal Husbandry Marine Transportation Studies Other Agriculture and Fishery
Art and Kinesiology
General Arts Design Fine Arts Cosmetology Photography Music Fashion Kinesiology Performing Media Arts Other Arts and Kinesiology
Interdisciplinary Studies
Interdisciplinary Research Science and Technology Studies Brain and Cognitive Science Technology Policy Other Interdisciplinary Studies

KOR

Growth Inhibitory Effect of Extracts of Propolis on Epithelial Ovarian Cancer Cells
Recommendations
Search
Questions

상피성 난소암 세포에서 프로폴리스 추출물의 세포 증식 저해 효과

논문 기본 정보

Type
Academic journal
Author
Yang Ga Ram (부산대학교) Yoon Kyung Mi (부산대학교) Oh Hyun Ho (부산대학교) Kim Min Sung (부산대학교) Hwang Tae Ho (부산대학교) An Won Gun (부산대학교)
Journal
Korean Society Of Life Science Journal of Life Science Vol.27 No.7 KCI Accredited Journals
Published
2017.7
Pages
834 - 839 (6page)

Usage

cover
📌
Topic
📖
Background
🔬
Method
🏆
Result
Growth Inhibitory Effect of Extracts of Propolis on Epithelial Ovarian Cancer Cells
Ask AI
Recommendations
Search
Questions

Abstract· Keywords

Report Errors
Propolis is a natural product collected from plants by honey bees product used extensively in traditional medicine for its antioxidant, anti-inflammatory, immunomodulatory and anti-cancer effects. Propolis exhibits a broad spectrum of biological activities because it is a complex mixture of natural substances. Ovarian cancer is the second most common newly diagnosed cancer from all cancers among women in Korea and the leading cause of death from gynecological malignancies. While most ovarian cancer patients initially respond to surgical debulking and chemotherapy, patients later succumb to the disease. Thus, there is an urgent need to test novel therapeutic agents to counteract the high mortality rate associated with ovarian cancer. In this study, we investigated the anti-cancer properties and the active mechanism of Australian propolis in human epithelial ovarian cancer A2780 cells. Our data revealed that propolis showed a cytotoxic activity in a dose-dependent manner. Flow cytometric analysis for cell cycle arrest and apoptosis using propidium iodide staning and annexin V-FITC indicated that propolis could induce cycle arrest in the G0/G1 phase and apoptosis in a dose-dependent manner on human epithelial ovarian cancer cells. These results suggest that the Australian propolis is potential alternative agent on ovarian cancer prevention and treatment.
#A2780 #anti-cancer effects #apoptosis #cell cycle arrest #propolis

Contents

서론
재료 및 방법
결과 및 고찰
감사의 글
References
초록

References (36)

Add References
Alencar, S. M., Oldoni, T. L., Castro, M. L., Cabral, I. S., Costa-Neto, C. M., Cury, J. A., Rosalen, P. L. and Ikegaki, M. 2007. Chemical composition and biological activity of a new type of Brazilian propolis: red propolis. J. Ethnoph. 113, 278-283. Aletti, G. D., Gallenberg, M. M., Cliby, W. A., Jatoi, A. and Hartmann, L. C. 2007. Current management strategies for ovarian cancer. Mayo Clin. Proc. 82, 751-770. Ashkenazi, A. 2008. Targeting the extrinsic apoptosis pathway in cancer. Cytokine Growth Factor Rev. 19, 325-331. Awale, S., Li, F., Onozuka, H., Esumi, H., Tezuka, Y. and Kadota, S. 2008. Constituents of Brazilian red propolis and their preferential cytotoxic activity against human pancreatic PANC-1 cancer cell line in nutrient-deprived condition. Bioorg. Med. Chem. 16, 181-189. Banskota, A. H., Tezuka, Y. and Kadota, S. 2001. Recent progress in pharmacological research of propolis. Phytother. Res. 15, 561-571.

Recommendations

It is an article recommended by DBpia according to the article similarity. Check out the related articles!

Related Authors

Frequently Viewed Together

Effects on the Risk of Cardiovascular Disease in Breast Cancer Patients Received Postoperative Adjuvant Anticancer Therapy
Yu ,  Mi-Seon ,  Lee Journal of the Korea Academia-Industrial cooperation Society 2014 .05
Influence of Sleep Disturbance and Depression on Quality of Life in Ovarian Cancer Patients during Chemotherapy
Yu ,  Sun-Young ,  Nho Asian Oncology Nursing 2015 .12
Changes of Symptom Distress and Quality of Life in Breast Cancer Patients Receiving Adjuvant Therapy
Pa ,  k ,  Jin-Hee Asian Oncology Nursing 2015 .06
The Effects of flexor and extensor strengthening exercise on Upper limb in Breast cancer related Lymphedema
Ha ,  Hae-Jung ,  Ahn Korean Journal of Sports Science 2014 .08
Influence of a regular aerobic exercise on body composition and immune cell in breast cancer patients undergoing surgery
Choi ,  Pil-Byung Korean Journal of Sports Science 2013 .08

Recently viewed articles

Case Study on Cross-examination Judicial Interpretation: Focused on Discourse Analysis of Chinese Judicial Interpretation
Lee Yoojin2021
 Effects of Sensory Integration Intervention Combined With App-Based Visual Perception Training on Attention, Visual Perception Ability, and Daily Living Ability of Children With Developmental Disabilities
Kwon Mi-hwa2021.12
 The Choi Family Murder during the 1980 Gwangju Uprising: War, Genocide, and Memory
Kim, Jeong-hanYuksabipyungsa2013.02

Comments(0)

0

Write first comments.

UCI(KEPA) : I410-ECN-0101-2018-470-001180786