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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.6
- 수록면
- 138 - 143 (6page)
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To investigate the efficacy of extract of Ginkgo Biloba seeds in high fat diet (HFD) in mice, the Ginkgo Biloba seeds extract (GSE) was orally administered to mice with a HFD at 300 mg/kg/day for 4 weeks. Our results show that GSE significantly inhibited fat accumulation. Moreover, GSE markedly reduced the final body weight with a decrease in epididymal adipose tissue mass and adipocyte size compared with the untreated HFD-induced group. Additionally, GSE ameliorated serum high-density lipoprotein cholesterol levels. The results show that Ginkgo Biloba seeds possesses hypocholesterolemic effect through down regulating lipid metabolism. Further studies are required in this area to strengthen the anti-obesity effects of GSE with active component, and it can be used a pro-drug instead of whole extract.
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참고문헌 (15)
참고문헌 신청
Bruno R, Dugan C, Smyth J, DiNatale D, Koo S. Green tea extract protects leptin-deficient, spontaneously obese mice from hepatic steatosis and injury. American Society for Nutrition. 2008: 21: 323-331.
Deng Q, Wang L, Wei F, Xie B, Huang F-H, Huang W, Shi J, Huang Q, Tian B, Xue S. Functional properties of protein isolates, globulin and albumin extracted from Ginkgo biloba seeds. Food Chemistry. 2011. 124: 1458-1465.
Gotto AM. Antioxidants, statins, and atherosclerosis. Journal of the American College of Cardiology. 2003. 41: 1205-1210.
Evans JR. Ginkgo biloba extract for age-related macular degeneration. Cochrane Database Systemic Review. 2013. 31: CD001775.
Klingenberg R, Hansson GK. Treating inflammation in atherosclerotic cardiovascular disease: emerging therapies. European Heart Journal. 2009. 30: 2838-2844.
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UCI(KEPA) : I410-ECN-0101-2018-510-001017663