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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2010.12
- 수록면
- 145 - 150 (6page)
이용수
초록· 키워드
오류제보하기
Lactobacillus species have been widely used in both human and animals to prevent or treat gastrointestinal disorders. Recently, it was reported that Lactobacillus spp. inhibited infections by respiratory and gastroenteric viruses; however, its mechanism is not clear. Lactobacillus spp. play direct and indirect roles in the inhibitory effects of viral replication. 1) In vitro study: Highest protection effects were showed with the known probiotics L. rhamnosus GG (LGG) and L. casei Shirota against both rotavirus (RV) and transmissible gastroenteritis virus (TGEV). 2) In vivo study: L. acidophilus had significant immunopotentiating effects, and was therefore recommended for use as a safe oral adjuvant for rotavirus vaccines in pigs. Oral administration of lactobacilli, such as LGG and L. gasseri, might protect a host animal from influenza virus (IFV) infection. Polysaccharides are regarded to be potentially useful and biologically active as an ingredient for pharmaceutical uses due to a variety of biological activities. Especially, sulphated polysaccharides exhibit broad-spectrum antiviral activity against enveloped viruses in vitro. With respect to human immunodeficiency virus type 1 (HIV-1), its in vitro antiviral activity is, specifically, the inhibition of virus-cell attachment, the first step in the infection process. Recently, it was reported that sulphated polysaccharides exhibited antiviral activity against HBV, HCMV, HSV and IFV. In conclusion, Lactobacillus spp. and polysaccharides with antiviral activity against diverse viruses are potential candidates as ingredients for probiotics and medicine candidate for the prevention and treatment of viral infections in animals and humans.
목차
서론
1. Lactobacillus spp.에 의한 바이러스 저해
2. Polysaccharide에 의한 바이러스 저해
결론 및 고찰
참고문헌
참고문헌 (24)
참고문헌 신청
1. [학술지(정기간행물)] - Seo BJ / 2010 / Bile tolerant Lactobacillus reuteri isolated from pig feces inhibits enteric bacterial pathogens and porcine rotavirus / Vet Res Commun 34 : 323 ~ 33
2. [학술지(정기간행물)] - Olivares M / 2007 / Oral intake of Lactobacillus fermentum CECT5716 enhances the effect of influenza vaccination / Nutrition 23 : 254 ~ 60
3. [학술지(정기간행물)] - De Vrese M / 2005 / Probiotic bacteria stimulate virus-specific neutralizing antibodies following a booster polio vaccination / Eur J Nutr 44 : 406 ~ 13
4. [기타자료] - Sutherland IW / 1977 / Microbial exopolysacchride synthesis. In Extracellular microbial polysaccharides / ACS : 40 ~ 57
5. [학술지(정기간행물)] - Sutherland, IW / 1983 / Extracellular polysaccharides. In Biotechnolohgy. Vol.3 / Verlag Chemie : 533 ~ 74
2. [학술지(정기간행물)] - Olivares M / 2007 / Oral intake of Lactobacillus fermentum CECT5716 enhances the effect of influenza vaccination / Nutrition 23 : 254 ~ 60
3. [학술지(정기간행물)] - De Vrese M / 2005 / Probiotic bacteria stimulate virus-specific neutralizing antibodies following a booster polio vaccination / Eur J Nutr 44 : 406 ~ 13
4. [기타자료] - Sutherland IW / 1977 / Microbial exopolysacchride synthesis. In Extracellular microbial polysaccharides / ACS : 40 ~ 57
5. [학술지(정기간행물)] - Sutherland, IW / 1983 / Extracellular polysaccharides. In Biotechnolohgy. Vol.3 / Verlag Chemie : 533 ~ 74
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