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논문 기본 정보

자료유형
학술저널
저자정보
Hyeong-Woo Lee (University of Florida) Yoon-Joong Kang (Jungwon University) Shin-Hyeong Cho (Korea Centers for Disease Control and Prevention) Byoung-Kuk Na (Gyeongsang National University School of Medicine) Jhang Ho Pak (University of Ulsan College of Medicine Asan Medical Center) Ho-Woo Nam (Catholic University of Korea) Yun-Kyu Park (Inha University School of Medicine) Youngjoo Sohn (Kyung Hee University) Tong-Soo Kim (Inha University School of Medicine)
저널정보
대한기생충학열대의학회 Parasites, Hosts and Diseases The Korean Journal of Parasitology Vol.53 No.2
발행연도
2015.4
수록면
169 - 175 (7page)

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The relationship between anti-Plasmodium vivax circumsporozoite protein (CSP) antibody levels and the prevalence of malaria in epidemic areas of South Korea was evaluated. Blood samples were collected from inhabitants of Gimpo- si (city), Paju-si, and Yeoncheon-gun (county) in Gyeonggi-do (province), as well as Cheorwon-gun in Gangwon-do from November to December 2004. Microscopic examinations were used to identify malaria parasites. ELISA was used to quantitate anti-circumsporozoite protein (CSP) antibodies against P. vivax. A total of 1,774 blood samples were collected. The overall CSP-ELISA-positive rate was 7.7% (n=139). The annual parasite incidences (APIs) in these areas gradually decreased from 2004 to 2005 (1.09 and 0.80, respectively). The positive rate in Gimpo (10.4%, 44/425) was the highest identified by CSP-ELISA. The highest API was found in Yeoncheon, followed by Cheorwon, Paju, and Gimpo in both years. The positive rates of CSP-ELISA were closely related to the APIs in the study areas. These results suggest that seroepidemiological studies based on CSP may be helpful in estimating the malaria prevalence in certain areas. In addition, this assay can be used to establish and evaluate malaria control and eradication programs in affected areas.

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Abstract
INTRODUCTION
MATERIALS AND METHODS
RESULTS
DISCUSSION
REFERENCES

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