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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국식품영양과학회 Preventive Nutrition and Food Science Preventive Nutrition and Food Science Vol.19 No.3
- 발행연도
- 2014.9
- 수록면
- 156 - 163 (8page)
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We investigated the effects of a high-protein diet and resveratrol supplementation on immune cells changes induced by abdominal irradiation in rats. Female Wistar rats were divided into 5 groups: 1) control diet, 2) control diet with irradiation 3) 30% high-protein diet with irradiation, 4) normal diet with resveratrol supplementation and irradiation, and 5) 30% high-protein diet with resveratrol supplementation and irradiation. We measured blood protein and albumin concentrations, lipid profiles, white blood cell (WBC) counts, proinflammatory cytokine production, and splenocyte proliferation in rats that had been treated with a 17.5 Gy dose of radiation 30 days prior. A high-protein diet affected plasma total cholesterol and very low density lipoprotein-cholesterol levels, which were increased by the radiation treatment. In addition, the lymphocyte percentage and immunoglobulin M (IgM) concentration were increased, and the neutrophil percentage was decreased in rats fed a high-protein diet. Resveratrol supplementation decreased the triglyceride (TG) level, but increased the IgM concentration and splenocyte proliferation. Proinflammatory cytokine production was lower in rats fed a high-protein diet supplemented with resveratrol than in rats fed a control diet. The results of the present study indicate that high-protein diets, with or without resveratrol supplementation, might assist with recovery from radiation-induced inflammation by modulating immune cell percentages and cytokine production.
목차
ABSTRACT
INTRODUCTION
MATERIALS AND METHODS
RESULTS AND DISCUSSION
CONCLUSION
REFERENCES
참고문헌 (41)
참고문헌 신청
1. [학술지(정기간행물)] - Baur JA / 2006 / Therapeutic potential of resveratrol:the in vivo evidence / Nat Rev Drug Discov 5 : 493 ~ 506
2. [학술지(정기간행물)] - Iuga C / 2012 / Antioxidant activity of trans-resveratrol toward hydroxyl and hydro peroxyl radicals: a quantum chemical and computational kinetics study / J Org Chem 77 : 3868 ~ 3877
3. [학술지(정기간행물)] - Fauconneau B / 1997 / Comparative study of radical scavenger and antioxidant properties of phenolic compounds from Vitis vinifera cell cultures using in vitro tests / Life Sci 61 : 2103 ~ 2110
4. [학술지(정기간행물)] - Athar M / 2007 / Resveratrol: A review of preclinical studies for human cancer prevention / Toxicol Appl Pharmacol 224 : 274 ~ 283
5. [학술지(정기간행물)] - Lin KH / 2009 / Mechanisms of resveratrol-induced platelet apoptosis / Cardiovasc Res 83 : 575 ~ 585
2. [학술지(정기간행물)] - Iuga C / 2012 / Antioxidant activity of trans-resveratrol toward hydroxyl and hydro peroxyl radicals: a quantum chemical and computational kinetics study / J Org Chem 77 : 3868 ~ 3877
3. [학술지(정기간행물)] - Fauconneau B / 1997 / Comparative study of radical scavenger and antioxidant properties of phenolic compounds from Vitis vinifera cell cultures using in vitro tests / Life Sci 61 : 2103 ~ 2110
4. [학술지(정기간행물)] - Athar M / 2007 / Resveratrol: A review of preclinical studies for human cancer prevention / Toxicol Appl Pharmacol 224 : 274 ~ 283
5. [학술지(정기간행물)] - Lin KH / 2009 / Mechanisms of resveratrol-induced platelet apoptosis / Cardiovasc Res 83 : 575 ~ 585
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UCI(KEPA) : I410-ECN-0101-2015-510-002746352