지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2014.9
- 수록면
- 185 - 191 (7page)
이용수
초록· 키워드
오류제보하기
Statistical methods are frequently used in toxicology, yet it is not clear whether the methods employed by the studies are used consistently and conducted based on sound statistical grounds. The purpose of this paper is to describe statistical methods used in top toxicology journals. More specifically, we sampled 30 papers published in 2014 from Toxicology and Applied Pharmacology, Archives of Toxicology, and Toxicological Science and described methodologies used to provide descriptive and inferential statistics. One hundred thirteen endpoints were observed in those 30 papers, and most studies had sample size less than 10, with the median and the mode being 6 and 3 & 6, respectively. Mean (105/113, 93%) was dominantly used to measure central tendency, and standard error of the mean (64/113, 57%) and standard deviation (39/113, 34%) were used to measure dispersion, while few studies provide justifications regarding why the methods being selected. Inferential statistics were frequently conducted (93/113, 82%), with one-way ANOVA being most popular (52/93, 56%), yet few studies conducted either normality or equal variance test. These results suggest that more consistent and appropriate use of statistical method is necessary which may enhance the role of toxicology in public health.
목차
INTRODUCTION
MATERIALS AND METHODS
RESULTS
DISCUSSION
REFERENCES
참고문헌 (38)
참고문헌 신청
Schor, S. / 1966 / Statistical evaluation of medical journal manuscripts / JAMA 195:1123~1128
Ko, W. R. / 2014 / Inappropriate use of standard error of the mean when reporting variability of study samples: A critical evaluation of four selected journals of obstetrics and gynecology / Taiwan J. Obstet. Gynecol 53:26~29
Nagele, P. / 2003 / Misuse of standard error of the mean (sem) when reporting variability of a sample. A critical evaluation of four anaesthesia journals / Br. J. Anaesth 90:514~516
Altman, D.G. / 2005 / Standard deviations and standard errors / BMJ 331:903
U.S. Department of Health and Human Services FaDA, Center for Drug Evaluation and Research / 1998 / Guidance for Industry:E9 Statistical Principles for Clinical Trials :1~22
Ko, W. R. / 2014 / Inappropriate use of standard error of the mean when reporting variability of study samples: A critical evaluation of four selected journals of obstetrics and gynecology / Taiwan J. Obstet. Gynecol 53:26~29
Nagele, P. / 2003 / Misuse of standard error of the mean (sem) when reporting variability of a sample. A critical evaluation of four anaesthesia journals / Br. J. Anaesth 90:514~516
Altman, D.G. / 2005 / Standard deviations and standard errors / BMJ 331:903
U.S. Department of Health and Human Services FaDA, Center for Drug Evaluation and Research / 1998 / Guidance for Industry:E9 Statistical Principles for Clinical Trials :1~22
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UCI(KEPA) : I410-ECN-0101-2015-510-002798785