지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2014.12
- 수록면
- 283 - 289 (7page)
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초록· 키워드
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Tea flavonoids and polyphenols are well known for their extraordinary antioxidant activity which is considered important for anti-aging processes in animals. This study evaluated the anti-wrinkle effects of three different kinds of tea (Camellia sinensis) water extracts (CSWEs) including green, white, and black teas using a photoaged hairless mouse model. Data showed that the CSWE-treatment greatly improved skin conditions of mice suffering from UVB-induced photoaging, based on the parameters including the skin erythema index, moisture capacity, and transepidermal water loss. In addition, the wrinkle measurement and image analysis of skin replicas indicated that CSWEs remarkably inhibited wrinkle formation. In histological examination, the CSWE-treated mice exhibited diminished epidermal thickness and increased collagen and elastic fiber content, key signatures for skin restoration. Furthermore, the reduced expression of MMP-3, a collagen-degradative enzyme, was observed in the skin of CSWE-treated animals. Interestingly, comparative data between green, white, and black tea indicated that the anti-wrinkle activity of white tea and black tea is equally greater than that of green tea. Taken together, these data clearly demonstrated that CSWEs could be used as an effective anti-wrinkle agent in photoaged animal skin, implying their extended uses in therapeutics.
목차
INTRODUCTION
MATERIALS AND METHODS
RESULTS
DISCUSSION
REFERENCES
참고문헌 (30)
참고문헌 신청
Fisher, G. J. / 1997 / Pathophysiology of premature skin aging induced by ultraviolet light / N. Engl. J. Med 337:1419~1428
Zhaorigetu, S. / 2003 / Inhibitory effects of silk protein, sericin on UVB-induced acute damage and tumor promotion by reducing oxidative stress in the skin of hairless mouse / J. Photochem. Photobiol. B 71:11~17
Chaquour, B. / 1995 / Chronic UVB and all trans retinoic acid induced qualitative and quantitative changes in hairless mouse skin / J. Photochem. Photobiol. B 28:125~135
Honda, A. / 2008 / Interleukin-1beta and macrophage migration inhibitory factor (MIF) in dermal fibroblasts mediate UVA-induced matrix metalloproteinase-1 expression / J. Dermatol. Sci 49:63~72
Varani, J. / 1991 / A direct comparison of pharmacologic effects of retinoids on skin cells in vitro and in vivo / Skin Pharmacol. Physiol 4:254~261
Zhaorigetu, S. / 2003 / Inhibitory effects of silk protein, sericin on UVB-induced acute damage and tumor promotion by reducing oxidative stress in the skin of hairless mouse / J. Photochem. Photobiol. B 71:11~17
Chaquour, B. / 1995 / Chronic UVB and all trans retinoic acid induced qualitative and quantitative changes in hairless mouse skin / J. Photochem. Photobiol. B 28:125~135
Honda, A. / 2008 / Interleukin-1beta and macrophage migration inhibitory factor (MIF) in dermal fibroblasts mediate UVA-induced matrix metalloproteinase-1 expression / J. Dermatol. Sci 49:63~72
Varani, J. / 1991 / A direct comparison of pharmacologic effects of retinoids on skin cells in vitro and in vivo / Skin Pharmacol. Physiol 4:254~261
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UCI(KEPA) : I410-ECN-0101-2016-513-001047906