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논문 기본 정보

자료유형
학술저널
저자정보
이상일 (계명문화대학) 이예경 (명지대학교) 김순동 (명지대학교) 이지언 (명지대학교) 최종근 (청운대학교) 박종필 (명지대학교) 임종환 (명지대학교) 서주원 (명지대학교) 이인애 (명지대학교)
저널정보
한국영양학회 Journal of Nutrition and Health Journal of Nutrition and Health Vol.46 No.6
발행연도
2013.12
수록면
493 - 502 (10page)

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In this study, we designed to confirm the dietary effect of anti-obesity of fermented soybean curd residue (FSCR; SCRMeju; Biji-meju) by A. oryzae, which is well known as a Korean traditional meju microbe. We observed that body weight gain, serum and hepatic lipid profile, as well as the activity of ROS generating enzyme and ROS scavenging enzyme in high-fat diet induced obese mice fed experimental diet (SCR and SCR-meju). Body weight gain and epididymal fat weight of HC (high-fat diet control) was markedly higher than that of NC (Normal control). Conversely, body weight gain and epididymal fat weight of the SCR (Biji) and SCR-meju (Biji-meju) group was significantly lower than that of HC; these of the SCR-meju group was lower than that of the SCR group. Furthermore, serum TG and total-cholesterol and LDLcholesterol contents of SCR and SCR-meju groups were lower than that of HC, and HDL-cholesterol level of the SCRmeju group was significantly higher than that of HC. In conclusion, although precise mechanisms of the antiobese effects of SCR-meju in this study are unknown, the present study provides an experimental evidence that SCR-meju may prevent obesity and obesity related metabolic syndromes, such as hyperlipidemia, hypertension and diabetes, and liver disease by high-fat diet. Nevertheless, further study in this filed will be needed.

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UCI(KEPA) : I410-ECN-0101-2015-590-001066864