지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
Uwhangchungsim-won (UC) has been used in various medical fields such as stroke, hypertension, atherosclerosis, autonomic imbalance and mental instability, etc. The aim of this study was to evaluate the effect of UC on cerebral hemodynamics and estimate the appropriate dose of UC.
Methods: We studied changes of hyperventilation-induced cerebrovascular reactivity and mean blood flow velocity of middle cerebral arteries (MCA) using transcranial Doppler. We observed the changes of mean blood pressure, pulse rate and expiratory CO2 using S/5 Compact Anesthesia Monitor from 10 healthy young volunteers who were administered UC twice a day in the 1st section and then once a day in the 2nd section.
Results: Mean blood pressure tended to decrease at 1 hour and pulse rate tended to decrease at 2 hours after second administration. After 2 hours, mean blood pressure rose to state before administration, but pulse rate maintained from 2 hours to 4 hours. The changes were not statistically significant.
Cerebral blood flow velocity in middle cerebral artery was not statistically significant after second administration. Cerebrovascular reactivity increased from 2 hours to 4 hours after second administration.
Conclusions: This study provides that administration of UC twice a day is more effective on hyperventilation-induced cerebrovascular reactivity than administration of UC once a day.
Methods: We studied changes of hyperventilation-induced cerebrovascular reactivity and mean blood flow velocity of middle cerebral arteries (MCA) using transcranial Doppler. We observed the changes of mean blood pressure, pulse rate and expiratory CO2 using S/5 Compact Anesthesia Monitor from 10 healthy young volunteers who were administered UC twice a day in the 1st section and then once a day in the 2nd section.
Results: Mean blood pressure tended to decrease at 1 hour and pulse rate tended to decrease at 2 hours after second administration. After 2 hours, mean blood pressure rose to state before administration, but pulse rate maintained from 2 hours to 4 hours. The changes were not statistically significant.
Cerebral blood flow velocity in middle cerebral artery was not statistically significant after second administration. Cerebrovascular reactivity increased from 2 hours to 4 hours after second administration.
Conclusions: This study provides that administration of UC twice a day is more effective on hyperventilation-induced cerebrovascular reactivity than administration of UC once a day.
목차
서론
연구방법
연구결과
고찰
결론
참고문헌
참고문헌 (27)
참고문헌 신청
1. [단행본] - 陳師文 / 1975 / 太平惠民和劑局方 / 族風出版社 : 3 ~
2. [학술지(정기간행물)] - Hong ND / 1987 / Studies on the Efficacy of Combined Preparation of Crude Drugs(XXXV) Effect of Woohwangchungsimwon on the Cardiovascular System / Natural Product Sciences 18 (4) : 241 ~ 248
3. [학술대회논문] - So CS / 1998 / Vitro Characterization of the Vasodilating Action of Woo Hwang Chung Sim Won(Niu Hung Win Xing Wan) / The 9th international congress of oriental medicine(The 9th ICOM)
4. [학위논문] - 고용석 / 1976 / 牛黃淸心元이 평활근에 미치는 영향 / 경희대학교대학원
5. [학술지(정기간행물)] - Sang Gyung Nam / 1990 / Experimental Studies on The Effect of Woohwangchungsimwon and Sohaphyangwon / The Journal of Kyung Hee University Medical Center 6 (2) : 220 ~ 237
2. [학술지(정기간행물)] - Hong ND / 1987 / Studies on the Efficacy of Combined Preparation of Crude Drugs(XXXV) Effect of Woohwangchungsimwon on the Cardiovascular System / Natural Product Sciences 18 (4) : 241 ~ 248
3. [학술대회논문] - So CS / 1998 / Vitro Characterization of the Vasodilating Action of Woo Hwang Chung Sim Won(Niu Hung Win Xing Wan) / The 9th international congress of oriental medicine(The 9th ICOM)
4. [학위논문] - 고용석 / 1976 / 牛黃淸心元이 평활근에 미치는 영향 / 경희대학교대학원
5. [학술지(정기간행물)] - Sang Gyung Nam / 1990 / Experimental Studies on The Effect of Woohwangchungsimwon and Sohaphyangwon / The Journal of Kyung Hee University Medical Center 6 (2) : 220 ~ 237
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UCI(KEPA) : I410-ECN-0101-2014-519-000284327