Palliative Hepatectomy for Advanced Hepatocellular Carcinoma with Multiple Metastases : A Case Report :A Case Report

Jae-myeong Lee; Kwang- Min Park; Julian Choi; Sang-Hoon Chon; Dae Wook Hwang; Young-Joo Lee

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자료유형: 학술저널

저자정보: Jae-myeong Lee (Ajou University School of Medicine) Kwang- Min Park (University of Ulsan College of Medicine) Julian Choi (University of Ulsan College of Medicine) Sang-Hoon Chon (University of Ulsan College of Medicine) Dae Wook Hwang (University of Ulsan College of Medicine) Young-Joo Lee (University of Ulsan College of Medicine)

저널정보: 한국간담췌외과학회 Annals of Hepato-Biliary-Pancreatic Surgery 한국간담췌외과학회지 제13권 제4호

발행연도: 2009.12

수록면: 295 - 300 (6page)

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Non-surgical treatment is usually performed for the cases of hepatocellular carcinoma (HCC) that are not suitable for curative treatment, such as those cases with a large tumor size with an insufficient hepatic remnant after resection, those cases with extensive and multifocal bilobar tumors or those cases with extrahepatic metastases of the disease. However, in this case report we present a case of palliative hepatectomy for treating advanced HCC with multiple metastases and the patient has had an excellent 1-year follow-up outcome. A 71-year-old man was referred to our hospital and the imaging studies showed a 10 cm mass in the right liver, with multiple variable sized masses in both lungs and a 1 cm nodule in the left adrenal gland. A lung biopsy revealed HCC; therefore, the working diagnosis was HCC with multiple lung metastases and a left adrenal gland adenoma or metastasis. We expected the cause of death would be deterioration of the hepatic function as the liver mass increased in size. Therefore, we performed a palliative right trisectionectomy for the primary liver mass. After recovery from the hepatectomy, the patient was managed with sorafenib. During the 1-year follow-up period after palliative hepatectomy, the patient is still alive with a good general performance status and no evidence of intrahepatic recurrence, even though there has been an aggravation of the lung metastases in size and number, and a slight increase in the size of the left adrenal gland. We suggest that in highly selected patients with advanced HCC and multiple extrahepatic metastases, and especially in the cases involving a large HCC with mild liver cirrhosis and a good general performance status, an aggressive treatment strategy with palliative hepatectomy can be an optional treatment modality to improve the overall survival.

#Hepatocellular carcinoma #Metastasis #Palliative treatment #Hepatectomy

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