지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2012.6
- 수록면
- 169 - 175 (7page)
이용수
초록· 키워드
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To search for the aldose reductase (AR) inhibitors from Korean folk plants, the inhibition of rat lens AR in vitro using the methanol (MeOH) extracts from Korean folk plants was investigated. Among fifty four Korean folk plants tested, the MeOH extract of Cedrela sinensis showed highest inhibition of AR (IC<SUB>50</SUB> value, 2.52 ㎍/ml). The plant C. sinensis has a possibility of new natural resources for the development of AR inhibitor for the prevention of diabetic complications.
목차
Abstract
Ⅰ. Introduction
Ⅱ. Materials and Methods
Ⅲ. Results and Discussion
Acknowledgements
References
참고문헌 (35)
참고문헌 신청
Min-Ji Bak / 2011 / Stimulation of Activity and Expression of Antioxidant Enzymes by Solvent Fractions and Isolated Compound from Cedrela sinensis Leaves in HepG2 Cells / Journal of Medicinal Food 14(4):405~412
Beyer-Mears A / 1985 / Reversal of diabetic cataract by sorbinil, an aldose reductase inhibitor / Diabetes 34:15~21
Beyer-Mears A / 1984 / Glomerular polyol accumulation in diabetes and its prevention by oral sorbinil / Diabetes 33:604~607
Bhatnagar A / 1992 / Aldose reductase: congenial and injurious profiles of an enigmatic enzyme / Biochem. Med. Metab. Biol 48:91~121
Chun-Whan Choi / 2007 / Antioxidant Constituents and a New Triterpenoid Glycoside from Flos Lonicerae / Archives of Pharmacal Research 30(1):1~7
Beyer-Mears A / 1985 / Reversal of diabetic cataract by sorbinil, an aldose reductase inhibitor / Diabetes 34:15~21
Beyer-Mears A / 1984 / Glomerular polyol accumulation in diabetes and its prevention by oral sorbinil / Diabetes 33:604~607
Bhatnagar A / 1992 / Aldose reductase: congenial and injurious profiles of an enigmatic enzyme / Biochem. Med. Metab. Biol 48:91~121
Chun-Whan Choi / 2007 / Antioxidant Constituents and a New Triterpenoid Glycoside from Flos Lonicerae / Archives of Pharmacal Research 30(1):1~7
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UCI(KEPA) : I410-ECN-0101-2013-480-002670245