지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2010.9
- 수록면
- 196 - 201 (6page)
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초록· 키워드
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Purpose: We evaluated the clinical implication of Resection A surgery retrospectively to identify whether quality of surgery can be used as a selection factor for adjuvant therapy in patients with gastric cancer.
Methods: Prognosis of 902 patients with gastric cancer who underwent Resection A surgery was evaluated.
Results: Among all discharged patients, 77 patients (8.5%) died of recurrent disease, 55 patients (6.1%) died without recurrent disease. Five-year survival rate of all discharged patients was 91.6% and 10-year survival rate 87.1%. Statistically significant prognostic factors were depth of invasion (P＜0.001), lymph node metastasis (P＜0.001), stage (P＜0.001), tumor location (P=0.036) and size (P=0.001), extent of gastric resection (P＜0.001), and chemotherapy (P＜0.001) on univariate analyses. However, depth of invasion (P=0.001), lymph node metastasis (P＜0.001), and total gastrectomy (P＜0.001) emerged as statistically significant poor prognostic factor on a multivariate analysis. Adjuvant chemotherapy did not increase the survival rate of patients after Resection A surgery, even in patients with stage Ⅱ disease.
Conclusion: In selecting the patients for adjuvant therapy, both the stage of gastric cancer and the quality of surgery should be considered.
Methods: Prognosis of 902 patients with gastric cancer who underwent Resection A surgery was evaluated.
Results: Among all discharged patients, 77 patients (8.5%) died of recurrent disease, 55 patients (6.1%) died without recurrent disease. Five-year survival rate of all discharged patients was 91.6% and 10-year survival rate 87.1%. Statistically significant prognostic factors were depth of invasion (P＜0.001), lymph node metastasis (P＜0.001), stage (P＜0.001), tumor location (P=0.036) and size (P=0.001), extent of gastric resection (P＜0.001), and chemotherapy (P＜0.001) on univariate analyses. However, depth of invasion (P=0.001), lymph node metastasis (P＜0.001), and total gastrectomy (P＜0.001) emerged as statistically significant poor prognostic factor on a multivariate analysis. Adjuvant chemotherapy did not increase the survival rate of patients after Resection A surgery, even in patients with stage Ⅱ disease.
Conclusion: In selecting the patients for adjuvant therapy, both the stage of gastric cancer and the quality of surgery should be considered.
목차
INTRODUCTION
METHODS
RESULTS
DISCUSSION
REFERENCES
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