지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2011.1
- 수록면
- 23 - 28 (6page)
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Purpose: In 2010, the new UICC/AJCC TNM classification for gastric cancer was declared. The new classification for gastric cancer has several changes from the 6th classification. We evaluated the prognostic values and differences according to the new UICC/AJCC TNM classification.
Methods: From 2000 to 2004, 1,196 patients who underwent curative resection with D1＋β or more lymph node dissection and with 15 or more lymph nodes retrieved were studied retrospectively. We analyzed clinical characteristics and survival outcomes retrospectively from medical records.
Results: According to UICC/AJCC 7th TNM classification, the 5-year survival rate (5YSR) of each group for depth of invasion and node metastasis were significantly different. The 5YSR of stage Ⅱ in 6th classification was 82.4% and the 5YSR of stage Ⅱa and Ⅱb in 7th classification were 92.2% and 82.9%. The 5YSR of stage Ⅲa and Ⅲb in 6th classification were 56.3% and 33.0%. The 5YSR of stage Ⅲa, Ⅲb and Ⅲc in 7th classification were 72.7%, 48.4% and 26.1%. In our Cox regression multivariate analysis, N stage of the 6th UICC/AJCC TNM classification was the main independent prognostic factor.
Conclusion: N stage of the 6th UICC/AJCC TNM classification is a more reliable prognostic factor than N stage of the 7th UICC/AJCC TNM classification. Further study should be performed to confirm the appropriateness of N stage TNM classification for gastric cancer.
Methods: From 2000 to 2004, 1,196 patients who underwent curative resection with D1＋β or more lymph node dissection and with 15 or more lymph nodes retrieved were studied retrospectively. We analyzed clinical characteristics and survival outcomes retrospectively from medical records.
Results: According to UICC/AJCC 7th TNM classification, the 5-year survival rate (5YSR) of each group for depth of invasion and node metastasis were significantly different. The 5YSR of stage Ⅱ in 6th classification was 82.4% and the 5YSR of stage Ⅱa and Ⅱb in 7th classification were 92.2% and 82.9%. The 5YSR of stage Ⅲa and Ⅲb in 6th classification were 56.3% and 33.0%. The 5YSR of stage Ⅲa, Ⅲb and Ⅲc in 7th classification were 72.7%, 48.4% and 26.1%. In our Cox regression multivariate analysis, N stage of the 6th UICC/AJCC TNM classification was the main independent prognostic factor.
Conclusion: N stage of the 6th UICC/AJCC TNM classification is a more reliable prognostic factor than N stage of the 7th UICC/AJCC TNM classification. Further study should be performed to confirm the appropriateness of N stage TNM classification for gastric cancer.
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REFERENCES
참고문헌 (17)
참고문헌 신청
1. [단행본] - Edge SB / 2010 / AJCC cancer staging manual. 7th ed / Springer
2. [단행본] - Greene FL / 2002 / American Cancer Society. AJCC cancer staging manual. 6th ed / Springer
3. [학술지(정기간행물)] - Lu Y / 2008 / Prognostic significance of subclassification of pT2 gastric cancer: a retrospective study of 847 patients / Surg Oncol 17 : 317 ~ 322
5. [학술지(정기간행물)] - Park DJ / 2007 / Subclassification of pT2 gastric adenocarcinoma according to depth of invasion (pT2a vs pT2b) and lymph node status (pN) / Surgery 141 : 757 ~ 763
6. [학술지(정기간행물)] - Ishigami S / 2004 / Clinical merit of subdividing gastric cancer according to invasion of the muscularis propria / Hepatogastroenterology 51 : 869 ~ 871
2. [단행본] - Greene FL / 2002 / American Cancer Society. AJCC cancer staging manual. 6th ed / Springer
3. [학술지(정기간행물)] - Lu Y / 2008 / Prognostic significance of subclassification of pT2 gastric cancer: a retrospective study of 847 patients / Surg Oncol 17 : 317 ~ 322
5. [학술지(정기간행물)] - Park DJ / 2007 / Subclassification of pT2 gastric adenocarcinoma according to depth of invasion (pT2a vs pT2b) and lymph node status (pN) / Surgery 141 : 757 ~ 763
6. [학술지(정기간행물)] - Ishigami S / 2004 / Clinical merit of subdividing gastric cancer according to invasion of the muscularis propria / Hepatogastroenterology 51 : 869 ~ 871
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