지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2007.8
- 수록면
- 641 - 645 (5page)
이용수
초록· 키워드
오류제보하기
Delphinidin, an aglycone form of anthocyanins, was demonstrated to have anti-carcinogenic potential. The compound at 50 μg/mL caused a significant increase of quinone reductase activity, an anti-carcinogenic marker enzyme, in mouse hepatoma cell lines (Hepa1c1c7 and BPRc1). Delphinidin enhanced the expression of other detoxifying or antioxidant enzymes including glutathione S-transferase, gamma-glutamylcysteine synthetase, heme oxygenase 1, and glutathione reductase. It suppressed the proliferation of murine hepatoma cells in a dose-dependent manner, with approximately IC<sub>50</sub> of 70 μg/mL. These results suggest that delphinidin might be useful for cancer prevention.
목차
Abstract
Introduction
Materials and Methods
Results and Discussion
Acknowledgments
References
참고문헌 (20)
참고문헌 신청
Nyman NA , 2001 , Determination of anthocyanidins inberries and red wine by high-performance liquid chromatography 49 : 4183 ~ 4187
Kowalczyk E , 2003 , Anthocyanins in medicine 55 : 699 ~ 702
Choung MG , 2001 , Isolation and determination of anthocyanins in seed coatsof black soybean (Glycine max L. Merr.) 49 : 5848 ~ 5851
Beninger CW , 2003 , Antioxidant activity of extracts,condensed tannin fractions, and pure flavonoids from Phaseolusvulgaris L. seed coat color genotypes 51 : 7879 ~ 7883
Jaiswal AK , 2004 , Regulation of antioxidant response element-dependentinduction of detoxifying enzyme synthesis 378 : 221 ~ 238
Kowalczyk E , 2003 , Anthocyanins in medicine 55 : 699 ~ 702
Choung MG , 2001 , Isolation and determination of anthocyanins in seed coatsof black soybean (Glycine max L. Merr.) 49 : 5848 ~ 5851
Beninger CW , 2003 , Antioxidant activity of extracts,condensed tannin fractions, and pure flavonoids from Phaseolusvulgaris L. seed coat color genotypes 51 : 7879 ~ 7883
Jaiswal AK , 2004 , Regulation of antioxidant response element-dependentinduction of detoxifying enzyme synthesis 378 : 221 ~ 238
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UCI(KEPA) : I410-ECN-0101-2013-573-001023359