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자료유형
학술저널
저자정보
저널정보
한국실험동물학회 Laboratory Animal Research Laboratory Animal Research Vol.25 No.4
발행연도
2009.12
수록면
347 - 353 (7page)

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The present study was carried out to investigate whether dietary supplementation of Pleurotus eryngii to the purified diet containing high fat (16%) and cholesterol (0.3%) could affect blood lipid profiles, liver fat contents, adiposity and intestinal digestive enzymes. A total of 48 male SD rats were allotted into three dietary treatments: (1) control (CON), 5% cellulose (CELL), and 5% Pleurotus eryngii (PLEU) groups. As a result of the experiment for 8 weeks, there was no difference in growth performance among the SD rats fed the diets supplemented with cellulose and Pleurotus eryngii compared with those fed the control diet. However, the PLEU group showed a significantly lower (P<0.05) abdominal fat deposition compared with the CON and CELL groups. The level of NEFA (non-esterified fatty acid), cholesterol and LDL-cholesterol in blood significantly decreased (P<0.05) in the SD rats fed the diet containing 5% Pleurotus eryngii. Hepatic lipid content was also markedly lower (P<0.05) in the PLEU group compared with the other groups. As regarding intestinal enzymes, the specific activity of maltase was remarkably reduced (P<0.05) in the PLEU group. However, the specific activities of sucrase, alkaline phosphatase and leucine aminopeptidase were not affected by dietary sources of fiber. This study suggests that dietary Pleurotus eryngii plays a potential role in down-regulation of adiposity via altering lipid metabolism and digestion of carbohydrate in SD rats.

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