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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2009.3
- 수록면
- 79 - 85 (7page)
이용수
초록· 키워드
오류제보하기
Animal models of disease are animals that mimic the pathological condition or the disease entity of specific diseases occurring in humans. These animals are very useful to screen drugs that may be harmful, have a side effect, or would allow a better understanding of the disease mechanism. This study surveyed the current situation of animal care and use program for the Genetic Engineered Mouse (GEM) in the possession of advanced country. Also, the items of these situation involved the GEM number, the national policy and the government support system. The largest number of disease animals in the world is maintained in the USA. Specifically, the National Institute of Health (NIH) in USA supports the several institutions such as Mutant Mouse Regional Resource Centers (MMRRC), Induced Mutant Resource (IMR), Mouse Mutant Gene Resource (MMR), Special Mouse Strains Resource (SMSR) and Neuromice (NMICE) to maintain the animal models of disease. In Japan, RIKEN BioResource Center as one of several resources centers is collecting, supplying and reserving GEM involving the animal models of disease. These works were supported by National BioResource Project (NBRP) of Japanese government. Finally, the some countries in the European Union compile theEuropean Mouse Mutant Archive (EMMA) in order to effectively support and manage these animal models of disease. At present, EMMA possesses 800 kinds of GEM disease models. Therefore, these results suggested that it is very important to establish the national management program for animal model of disease, and this system must be established as soon as possible in our country.
목차
재료 및 방법
결과
고찰
감사의 글
참고문헌
참고문헌 (18)
참고문헌 신청
1. [인터넷자원] - / / Center for Animal Resources and Development
2. [단행본] - Chae, K.R. / 2006 / Methods of transgenic mice using microinjection technique / Kukjin P&D com : 3 ~ 8
3. [학술지(정기간행물)] - Clark, A.J. / 1998 / Gene expression in the mammary glands of transgenic animals / Biochem. Soc. Symp 63 : 133 ~ 140
4. [인터넷자원] - / / European Mouse Mutant Archive
5. [인터넷자원] - / / Federation of International Mouse Resources
2. [단행본] - Chae, K.R. / 2006 / Methods of transgenic mice using microinjection technique / Kukjin P&D com : 3 ~ 8
3. [학술지(정기간행물)] - Clark, A.J. / 1998 / Gene expression in the mammary glands of transgenic animals / Biochem. Soc. Symp 63 : 133 ~ 140
4. [인터넷자원] - / / European Mouse Mutant Archive
5. [인터넷자원] - / / Federation of International Mouse Resources
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UCI(KEPA) : I410-ECN-0101-2009-510-019510750