지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2008.12
- 수록면
- 203 - 210 (8page)
이용수
초록· 키워드
오류제보하기
One of cell surface receptor proteins, human folate receptor (hFR) involves in the uptake of folates through cell membrane into cytoplasm, and is anchored to the plasma membrane by a fatty acid linkage, which has been identified in some cells as a glycosylphosphatidylinositol (GPI)-tailed protein with a molecular mass of about 40 kDa. The hFR is released by phosphatidylinositol phospholipase C (PI-PLC) because it contains fatty acids and inositol on the GPI tail. Caveolin decorates the cytoplasmic surface of caveolae and has been proposed to have a structural role in maintaining caveolae. It is unknown whether caveolin is involved in targeting, and is necessary for the function of GPI-tailed proteins. To compare the ability of folic acid binding, internalization and expression of hFR, and the effect of caveolin at the both apical and basolateral side of cell surfaces in Chinese hamster ovary (CHO) clone cells overexpressed the hFR and/or caveolin. Our present results suggest a possibility that the overexpression of caveolin does not be involved in expression of hFR, but plays a role as a factor in PI-PLC releasing kinetics, and for a regulation of formation, processing and function of hFR in CHO clone cells overexpressed caveolin.
목차
INTRODUCTION
MATERIALS AND METHODS
RESULTS
DISCUSSION
Acknowledgements
REFERENCES
참고문헌 (42)
참고문헌 신청
1. [학술지(정기간행물)] - Antony AC / 1992 / The biological chemistry of folate receptors / Blood 79 : 2807 ~ 2820
2. [학술지(정기간행물)] - Antony AC / 1996 / Folate receptors / Annu Rev Nutr 16 : 501 ~ 521
3. [학술지(정기간행물)] - Bagnoli M / 2000 / Down modulation of caveolin-1 expression in human ovarian carcinoma is directly related to alpha-folate receptor over expression / Oncogene 19 : 4754 ~ 4763
4. [학술지(정기간행물)] - Buist MR / 1995 / Distribution of OV-TL 3 and MOv18 in normal and malignant ovarian tissue / J Clin Pathol 48 : 631 ~ 636
5. [학술지(정기간행물)] - Chung KN / 1995 / Rapid turnover and impaired cell-surface expression of the human folate receptor in mouse L(tk-) fibroblasts, a cell line defective in glycosylphosphatidyl inositol tail synthesis / Arch Biochem Biophys 322 : 228 ~ 234
2. [학술지(정기간행물)] - Antony AC / 1996 / Folate receptors / Annu Rev Nutr 16 : 501 ~ 521
3. [학술지(정기간행물)] - Bagnoli M / 2000 / Down modulation of caveolin-1 expression in human ovarian carcinoma is directly related to alpha-folate receptor over expression / Oncogene 19 : 4754 ~ 4763
4. [학술지(정기간행물)] - Buist MR / 1995 / Distribution of OV-TL 3 and MOv18 in normal and malignant ovarian tissue / J Clin Pathol 48 : 631 ~ 636
5. [학술지(정기간행물)] - Chung KN / 1995 / Rapid turnover and impaired cell-surface expression of the human folate receptor in mouse L(tk-) fibroblasts, a cell line defective in glycosylphosphatidyl inositol tail synthesis / Arch Biochem Biophys 322 : 228 ~ 234
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
The Role of Caveolin-1 in Senescence and Ototoxicity of Differentiated Cochlear Hair Cell Line (UB/OC-1)
Molecular & cellular toxicology
2009 .01
-
Significance of Caveolin-1 Regulators in Pancreatic Cancer
Asian Pacific journal of cancer prevention : APJCP
2013 .01
-
The Loss of Expression of Caveolin-1 in Gastrointestinal Stromal Tumors
Journal of Pathology and Translational Medicine
2005 .01
-
근육 세포와 조직에서 Caveolin-3의 발현 양상
Annals of Rehabilitation Medicine
2003 .01
-
Ectopic Expression of Caveolin-1 Induces COX-2 Expression in Rabbit Articular Chondrocytes via MAP Kinase Pathway
Immune Network
2006 .09
-
Loss of Caveolin 1 is Associated With the Expression of Aquaporin 1 and Bladder Dysfunction in Mice
International Neurourology Journal
2015 .01
-
1980년 - 1987년 한국에서 발생한 신증후 출혈열 환자의 혈청학적 역학적 조사
JOURNAL OF BACTERIOLOGY AND VIROLOGY
1988 .12
-
Field Trial of HFRS Vaccine in Man
JOURNAL OF BACTERIOLOGY AND VIROLOGY
1989 .12
-
1996~1998년 유고슬라비아에서 실시한 한탄바이러스 불활화 백신 ( NantavaxTM) 의 면역효과에 대한 야외시험
JOURNAL OF BACTERIOLOGY AND VIROLOGY
1999 .06
-
Effects of Estrogens on the Expression of Caveolin-1 in the Urinary Bladders of Female Rats
International Neurourology Journal
2011 .01
-
The GPI-specific PLC that releases renal dipeptidase from the GPI-anchor is present in detergent-insoluble GPI-rich membrane domains
대한약학회 학술대회
2000 .01
-
Differential expression of caveolins and myosin heavy chains in response to forced exercise in rats
Laboratory Animal Research
2012 .03
-
Hemorrhagic Fever with Renal Syndrome
Infection and Chemotherapy
2019 .01
-
Characterization of Glycoproteins of Viruses Causing Hemorrhagic Fever with Renal Syndrome (HFRS) and Classification of HFRS-Related Viruses Using Monoclonal Antibodies
JOURNAL OF BACTERIOLOGY AND VIROLOGY
1986 .06
-
soluble 의 human folate receptor 의 folate 결합과 수송에 관한 특성 ( characterization of soluble type human folate receptor on folate binding and transport )
한국독성학회지
1998 .09
-
신증후 출혈열의 임상진단과 혈청진단
JOURNAL OF BACTERIOLOGY AND VIROLOGY
1987 .06
-
An Ototoxic Antibiotic Gentamicin Can Increase PKA-caveolin-1 Signaling Pathway in Differentiated Vestibular Cell Line (UB/UE-1)
Molecular & cellular toxicology
2008 .01
-
간세포암종에서 Caveolin의 발현: 종양의 신생동맥 형성과 영상소견의 연관성
Clinical and Molecular Hepatology
2007 .01
-
ERRATUM: Caveolin-1 Modulates Docetaxel-Induced Cell Death in Breast Cancer Cell Subtypes through Different Mechanisms
Cancer Research and Treatment
2019 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0