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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국식품영양과학회 Journal of Food Science and Nutrition Journal of Food Science and Nutrition Vol.13 No.4
- 발행연도
- 2008.12
- 수록면
- 281 - 285 (5page)
이용수
초록· 키워드
오류제보하기
Cherry tomatoes are rich in antioxidants, which may protect against neurodegeneration and consequent memory loss. This study was conducted to investigate the effect of cherry tomatoes on scopolamine-induced amnesia in mice. Male ICR mice (4 weeks old) were maintained for 4 weeks on a diet containing 10 or 20% tomato powder (TP), and then administered scopolamine (1 ㎎/㎏ body weight, i.p.) 45 min before memory testing. Passive avoidance and Morris water maze testing revealed that scopolamine-induced amnesia was significantly reduced in the TP groups compared to the non TP-received (control) group. Accordingly, acetylcholinesterase activities in the serum and brain of TP groups were lower than those in the control group. These findings suggest that cherry tomatoes may be useful for the prevention of neurodegenerative diseases such as amnesia and Alzheimer’s disease.
목차
Abstract
INTRODUCTION
MATERIALS AND METHODS
RESULTS AND DISCUSSION
ACKNOWLEDGEMENT
REFERENCES
참고문헌 (28)
참고문헌 신청
1. [학술지(정기간행물)] - Beatty WW / 1986 / Memory failure after scopolamine treatment: implications for cholinergic hypothesis of dementia / Behav Neural Biol 45 : 196 ~ 211
2. [학술지(정기간행물)] - Jones GMM / 1992 / Effects of acute subcutaneous nicotine on attention, information processing and short-term memory in Alzheimer's disease / Psychopharmacology 108 : 485 ~ 494
3. [학술지(정기간행물)] - Eidi M / 2003 / Effects of histamine and cholinergic systems on memory retention of passive avoidance learning in rats / Eur J Pharmacol 465 : 91 ~ 96
4. [학술지(정기간행물)] - Dunnett SB / 1985 / Transplantation of embryonic ventral forebrain neurons to the nucleus basalis magnocellularis : II. Sensorimotor and learning impairments / Neuroscience 16 : 787 ~ 797
5. [학술지(정기간행물)] - Levy ML / 1999 / Neuropsychiatric symptoms and cholinergic therapy for Alzheimer’s disease / Gerontol 45 : 15 ~ 22
2. [학술지(정기간행물)] - Jones GMM / 1992 / Effects of acute subcutaneous nicotine on attention, information processing and short-term memory in Alzheimer's disease / Psychopharmacology 108 : 485 ~ 494
3. [학술지(정기간행물)] - Eidi M / 2003 / Effects of histamine and cholinergic systems on memory retention of passive avoidance learning in rats / Eur J Pharmacol 465 : 91 ~ 96
4. [학술지(정기간행물)] - Dunnett SB / 1985 / Transplantation of embryonic ventral forebrain neurons to the nucleus basalis magnocellularis : II. Sensorimotor and learning impairments / Neuroscience 16 : 787 ~ 797
5. [학술지(정기간행물)] - Levy ML / 1999 / Neuropsychiatric symptoms and cholinergic therapy for Alzheimer’s disease / Gerontol 45 : 15 ~ 22
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