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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2007.3
- 수록면
- 19 - 24 (6page)
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초록· 키워드
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Non-human primate is the essential experimental systems in toxicology division since their homology for human make more reliable evaluation of toxicities than any other non-rodent species. Captive monkeys housed in individual-cage can be observed of the bizarre behavior such as self-biting behavior, stereotypical behavior, over-grooming, aggressive expression and so on. In those cases, many parameters can be affected to evaluate toxicology study results by monkey's condition such as stress, decrease of food consumption, body weight loss, hematological parameters and serum biochemistry parameters. In the non-human primate facility of Korea Institute of Toxicology, mingle cages were made from individual cages for offering the social environmental enrichment to prevent those bizarre behavior. Pair-housing was made for 9 weeks with 3-5 year-old 48 males and 42 females, and observed the clinical signs and body weight changes. In the results of this study, 91.7% of male cage mates and 100% of female cage mates were made successful pair-housing formation except 2 cases of male cage mates with serious injuries from fighting. And body weight gains were not changed between individual cage-housing and pair-housing for 9 weeks.
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재료 및 방법
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고찰
참고문헌
참고문헌 (19)
참고문헌 신청
Bennett , 1988 , Nonhumanprimates in biomedical research In Disease
Bennett, B.T , 1995 , Nonhuman primates in biomedical research. In Biology and Management
Bogaards, J.J.P , 2000 , Determining the best animal model for human cytochrome P450 activities: acomparison of mouse, rat, rabbit, dog, micropig, monkey and man 12 : 1131 ~ 1152
Fortman, J.D , 2002 , The Laboratory Nonhuman Primate
Gray, E.G , 1994 , Psychological well-being in paired adult female rhesus (Macaca mulatta) 33 : 89 ~ 99
Bennett, B.T , 1995 , Nonhuman primates in biomedical research. In Biology and Management
Bogaards, J.J.P , 2000 , Determining the best animal model for human cytochrome P450 activities: acomparison of mouse, rat, rabbit, dog, micropig, monkey and man 12 : 1131 ~ 1152
Fortman, J.D , 2002 , The Laboratory Nonhuman Primate
Gray, E.G , 1994 , Psychological well-being in paired adult female rhesus (Macaca mulatta) 33 : 89 ~ 99
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UCI(KEPA) : I410-ECN-0101-2009-510-016367782