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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2007.9
- 수록면
- 317 - 320 (4page)
이용수
초록· 키워드
오류제보하기
Myocardial infarction (MI) is one of the leading causes of death in advanced nations. The therapeutic option is limited for chronic heart failure which is the result of MI. Recently, it has been reported that adult cardomyocytes can proliferate although the proliferating ability is quite low. To find clues for efficient induction of myocardial proliferation in heart with MI, we analyzed gene expression pattern in the heart with MI using microarray assay in mice. We found 17 and 8 genes of which the expression level increased and decreased in mouse heart with MI compared with those in normal ones, respectively. These alterations in the gene expressions reflect the heart under healing from MI. Therefore, further analysis for these genetic changes may helpful in future cell-based therapeutic application and induction of myocardial cell proliferation in patients with MI.
목차
Materials and Methods
Results and Discussion
Acknowledgment
References
참고문헌 (27)
참고문헌 신청
1. [학술지(정기간행물)] - Beltrami, A.P / 2001 / Evidence that human cardiac myocytes divide after myocardial infarction 344 : 1750 ~ 1757
2. [학술지(정기간행물)] - Bonaros, N / 2004 / Cell therapy for ischemic heart disease 46 : 13 ~ 23
3. [학술지(정기간행물)] - Brey, R.L / 2001 / beta(2)-Glycoprotein 1- dependent anticardiolipin antibodies and risk of ischemic stroke and myocardial infarction: the honolulu heart program 32 (8) : 1701 ~ 1706
4. [학술지(정기간행물)] - Cai, C.L / 2003 / Isl1 identifies a cardiac progenitor population that proliferates prior to differentiation and contributes a majority of cells to the heart 5 : 877 ~ 889
5. [학술지(정기간행물)] - Cho, Y.G / 2007 / Genetic Alterations of the ATBF1 Gene in Gastric Cancer 13 (5) : 4355 ~ 4359
2. [학술지(정기간행물)] - Bonaros, N / 2004 / Cell therapy for ischemic heart disease 46 : 13 ~ 23
3. [학술지(정기간행물)] - Brey, R.L / 2001 / beta(2)-Glycoprotein 1- dependent anticardiolipin antibodies and risk of ischemic stroke and myocardial infarction: the honolulu heart program 32 (8) : 1701 ~ 1706
4. [학술지(정기간행물)] - Cai, C.L / 2003 / Isl1 identifies a cardiac progenitor population that proliferates prior to differentiation and contributes a majority of cells to the heart 5 : 877 ~ 889
5. [학술지(정기간행물)] - Cho, Y.G / 2007 / Genetic Alterations of the ATBF1 Gene in Gastric Cancer 13 (5) : 4355 ~ 4359
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UCI(KEPA) : I410-ECN-0101-2009-510-016364296