지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2006.6
- 수록면
- 145 - 149 (5page)
이용수
초록· 키워드
오류제보하기
This study investigated whether estradiol modulates the heme oxygenase-1 (HO-1) and HO-2 expressions in brain ischemic injury. Adult female rats were ovariectomied and treated with estradiol prior to middle cerebral artery occlusion (MCAO). Brains were collected 24 h after MCAO and infarct volumes were analyzed. Estradiol administration significant-reduced infarct volume and decreased the positive cells of TUNEL staining in the cerebral cortex. Activation of HO-1 and HO-2 was measured using Western blot analysis. Estradiol increased the level of HO-1 in ischemic injury induced by MCAO. The level of HO-1 was 0.81 ± 0.15 and 0.97 ± 0.25 in the ipsilateral cortex of oil-and estradiol-treated animals, respectively. However, the level of HO-2 was consistently maintained in the ipsilateral cortex of oil- and estradiol-treated animals. Our findings suggest that estradiol prevents cell death caused by neuronal cell injury through the increase of HO-1 expression.
목차
Materials and Methods
Results
Discussion
Acknowledgment
References
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
17β-Estradiol Regulates Nitric Oxide Synthase Expression in Ischemic Brain Injury
Laboratory Animal Research
2008 .06
-
17β-Estradiol Attenuates a Reduction of Gamma-Enolase Following Cerebral Ischemic Injury
Laboratory Animal Research
2009 .06
-
Effects of Melatonin on Heme Oxygenase-1 in a Middle Cerebral Artery Occlusion Animal Model
Laboratory Animal Research
2008 .03
-
Estradiol Modulates Various Proteins in Middle Cerebral Artery Occlusion Animal Model-a Proteomics Approach
한국실험동물학회 학술발표대회 논문집
2014 .02
-
Estradiol Prevents Injury-Induced Reduction of Peroxiredoxin-2 in Brain Ischemia Models
Laboratory Animal Research
2009 .12
-
폐암세포주에서 Heme Oxygenase-1의 역할
Tuberculosis and Respiratory Diseases
2006 .01
-
17β-estradiol prevents the reduction in parvalbumin expression induced by ischemic brain injury
한국실험동물학회 학술발표대회 논문집
2014 .08
-
Up-regulation of Heme Oxygenase-1 Expression by cAMP-elevating Agents in RAW 264.7 cells
The journal of applied pharmacology : the official journal of the Korean Society of Applied Pharmacology
2002 .01
-
Solvent Effects on Physicochemical Behavior of Estradiols Recrystallized for Transdermal Delivery
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2008 .01
-
흰 쥐에서 난소 적출술로 유발한 골다공증에 대한 Estradiol의 효과
대한정형외과학회지
1994 .10
-
비용조직에서 Heme Oxygenase-1 발현에 대한 면역조직학적 연구
대한이비인후-두경부외과학회지
2005 .01
-
ICR mouse의 피부와 간에서 자외선 B파에 의한 Heme Oxygenase-1의 유도
한국환경보건학회지
2008 .01
-
Estradiol prevents the focal cerebral ischemic injury through mTOR/p70S6/S6 kinase signaling pathway
한국실험동물학회 학술발표대회 논문집
2008 .05
-
Estradiol prevents down-regulation of PEA-15 and its two phosphorylated forms in focal cerebral ischemia
한국실험동물학회 학술발표대회 논문집
2015 .02
-
Estradiol에 의해 유도되는 E2lG5 단백의 유방암 세포 주에 대한 작용
Annals of Surgical Treatment and Research
2005 .01
-
$17\beta$-estradiol의 고혈압 유도반응 억제와 인체적용 전기자극의 $17\beta$-estradiol 활성 증가
대한물리치료학회지(JKPT)
2009 .01
-
Serum Concentration of Estradiol and Estrone Following Oral Administration of Low-dose Hormone Therapy in Postmenopausal Korean Women
대한폐경학회지
2011 .01
-
새로운 내부 방사선 치료용 $^{166}Ho$-Chitosan 착물 및 그 응집입자의 제조에 관한 연구
대한핵의학회지
1996 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0
UCI(KEPA) : I410-ECN-0101-2009-510-016362929