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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국식품영양과학회 Journal of Food Science and Nutrition Journal of Food Science and Nutrition Vol.12 No.2
- 발행연도
- 2007.6
- 수록면
- 84 - 88 (5page)
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초록· 키워드
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In this study, we investigated antimutagenic and anticancer activities of leaf mustard (LM, Brassica juncea) and leaf mustard kimchi (LMK) during their fermentation period. Methanol extracts were prepared from raw mustard, brined leaf mustard in 10% Gueun salt solution for 2 hrs, leaf mustard fermented at 15℃ for 5 days after brined in 10% Guenun salt solution for 2 hrs (Fr-LM), fresh leaf mustard kimchi (Fresh-LMK) and optimally ripened leaf mustard kimchi fermented at 5℃ for 30 days (OR-LMK). OR-LMK showed the strongest inhibitory activities against the mutagenicities induced by aflatoxin B1 in Salmonella Typhimurium TA100. LMs and LMKs inhibited the survival or growth of AGS human gastric adenocarcinoma cells and HT-29 human colon carcinoma cells in MTT assay and growth inhibition test. Among the extracts, OR-LMK and FR-LM exhibited strong antiproliferative effect against cancer cells, especially HT-29 cells. DAPI staining assay showed that OR-LMK induced apoptosis cell death of HT-29 cells in a dose-dependent manner. These results suggest that leaf mustards and leaf mustard kimchi have chemopreventive activities.
목차
Abstract
INTRODUCTION
MATERIALS AND METHODS
RESULTS AND DISCUSSION
ACKNOWLEDGEMENTS
REFERENCES
참고문헌 (19)
참고문헌 신청
Park KY, Lee KI, Rhee SH. 1992. Inhibitory effects of green-yellow vegetables on mutagenecity in Samonella assay system and on the growth of AZ-521 human gastric cancer cells. J Korean Soc Food Nutr 21: 149-153.
Park KY, Yang HS, Rhee SH, Rhew TH. 1993 Isolation, identification and biochemical mode of the antimutagenic and antitumor compounds from yellow-green vegetables and traditional anticancer medical plants. KOSEF report 90-0500-03.
Lee KI, Park KY, Rhee SH. 1992. Antimutagenic effect of green-yellow vegetables toward aflatoxin B1 and 4-butriqyubikube-1-oxide. J Korean Soc Food Nutr 21: 143-148.
Lee KI. 1992. Inhibitory effects of green-yellow vegetables of mutagenecity induced by various mutagens and on the growth of human cancer cells. PhD Dissertation. Pusan National University, Busan.
Farrel KT. 1985. Spices. Condiments and Seasonings. Van Nostrant Company, New York. p 150-155.
Park KY, Yang HS, Rhee SH, Rhew TH. 1993 Isolation, identification and biochemical mode of the antimutagenic and antitumor compounds from yellow-green vegetables and traditional anticancer medical plants. KOSEF report 90-0500-03.
Lee KI, Park KY, Rhee SH. 1992. Antimutagenic effect of green-yellow vegetables toward aflatoxin B1 and 4-butriqyubikube-1-oxide. J Korean Soc Food Nutr 21: 143-148.
Lee KI. 1992. Inhibitory effects of green-yellow vegetables of mutagenecity induced by various mutagens and on the growth of human cancer cells. PhD Dissertation. Pusan National University, Busan.
Farrel KT. 1985. Spices. Condiments and Seasonings. Van Nostrant Company, New York. p 150-155.
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UCI(KEPA) : I410-ECN-0101-2009-511-016734819