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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2007.3
- 수록면
- 39 - 46 (8page)
이용수
초록· 키워드
오류제보하기
The aim of the study was to see if there is any differences in urinary 1-hydroxypyrene glucuronide (1-OHPG) and 2-naphthol levels in children (8~14 years old) and their mothers (30~46 years old) living three cities in South Korea (Seoul, Incheon and Pohang) and three in China (Changchun, Datong and Kunming), where the levels of air pollution varies. The factors related with urinary biomarkers levels were also evaluated. The study subjects consisted of 118 Korean (60 children and 58 their mothers) and 120 Chinese (60 children and 60 their mothers). Urinary 1-OHPG was measured by synchronous fluorescence spectroscopy after immuno-affinity purification using monoclonal antibody 8E11 and urinary 2-naphthol concentrations were determined by HPLC with fluorescence detector. Information on recent consumption of diet containing high PAHs, environmental tobacco smoke (ETS), type of cooking and heating fuels, and other life-style characteristics were collected by self-administered questionnaire. The arithmetic mean of urinary 1-OHPG levels (n = 120, mean ± SD, 6.77 ± 7.96 μmol/mol creatinine) in Chinese were 10 fold higher than those in Korean (n = 118, 0.62 ± 0.61 μmol/mol creatinine) (P ＜ 0.01). Urinary 2-naphthol levels in Chinese (n = 119, 59.50 ± 82.29 ㎍/g creatinine) were significantly higher than those in Korean (n = 117, 25.09 ± 46.56 ㎍/g creatinine) (P ＜ 0.01). Urinary 1-OHPG and 2-naphthol levels were significantly higher in children living the polluted cities in China (Datong and Chanchun, respectively). Multiple linear regression analysis indicated that living in factory area (vs. residential area) and use of coal stove as heating fuel were significant predictors for urinary 1-OHPG (overall model R<SUP>2</SUP> = 0.46, n = 204). And ETS was predictor for urinary 2-naphthol levels in Korean (R<SUP>2</SUP> = 0.36, n = 46). These results indicated that urinary 1-OHPG and 2-naphthol levels were related with different ambient particulate air pollution, type of heating fuels and ETS.
목차
서론
재료 및 방법
결과
고찰
감사의 글
참고문헌
참고문헌 (23)
참고문헌 신청
Bayer-Oglesby, L , 2005 , Decline of ambient air pollution levels and improved respiratory health in Swiss children 113 : 1632 ~ 1637
Delfino, R.J , 2004 , Association of FEV1 in asthmatic children with personal and microenvironmental exposure to airborne particulate matter 112 : 932 ~ 941
Dubowsky, S.D , 1999 , The contribution of traffic to indoor concentrations of polycyclic aromatic hydrocarbons 9 : 312 ~ 321
Fagundes, R.B , 2006 , Higher urine 1-hydroxy pyrene glucuronide (1-OHPG) is associated with tobacco smoke exposure and drinking mate in healthy subjects from Rio Grande do Sul, Brazil 6 : 139 ~
Hansen, A.M , 2006 , Urinary 1-hydroxypyrene in children living in city and rural residences in Denmark 363 : 70 ~ 77
Delfino, R.J , 2004 , Association of FEV1 in asthmatic children with personal and microenvironmental exposure to airborne particulate matter 112 : 932 ~ 941
Dubowsky, S.D , 1999 , The contribution of traffic to indoor concentrations of polycyclic aromatic hydrocarbons 9 : 312 ~ 321
Fagundes, R.B , 2006 , Higher urine 1-hydroxy pyrene glucuronide (1-OHPG) is associated with tobacco smoke exposure and drinking mate in healthy subjects from Rio Grande do Sul, Brazil 6 : 139 ~
Hansen, A.M , 2006 , Urinary 1-hydroxypyrene in children living in city and rural residences in Denmark 363 : 70 ~ 77
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UCI(KEPA) : I410-ECN-0101-2009-513-016602094