메뉴 건너뛰기
.. 내서재 .. 알림
소속 기관/학교 인증
인증하면 논문, 학술자료 등을  무료로 열람할 수 있어요.
한국대학교, 누리자동차, 시립도서관 등 나의 기관을 확인해보세요
(국내 대학 90% 이상 구독 중)
로그인 회원가입 고객센터 ENG
주제분류

추천
검색
질문

논문 기본 정보

자료유형
학술저널
저자정보
저널정보
한국독성학회 Toxicological Research Journal of Toxicology and Public Health Vol.23 No.1
발행연도
2007.3
수록면
11 - 17 (7page)

이용수

표지
📌
연구주제
📖
연구배경
🔬
연구방법
🏆
연구결과
AI에게 요청하기
추천
검색
질문

초록· 키워드

오류제보하기
This study was carried out to investigate the effect of LAB (Lactic acid bacteria: Lactobacillus acidophilus, Bifidobacterium bifidum and Streptococcus thermophilus) on detoxication of damaged liver in carbon tetrachloride (CCl₄) and ethanol (25%)-treated rats. Rats had been daily (twice a day) pretreated with saline (0.5 ㎖/㎏: untreated group), CCl₄ (0.5 ㎖/㎏: other groups) for 6 days. At seventh day, after treating rat with CCl₄ and then, mixture of LAB (10<SUP>11</SUP>/0.5 ㎖: LAB group), saline (0.5 ㎖/㎏: untreated group, CCl₄ group), and biphenyl dimethyl dicarboxylate (DDB) (50 ㎎/㎏: DDB group) were treated orally with CCl₄ for 8 days. Ethanol is treated as the same manner instead of CCl₄. To investigate the hepatoprotective effect, rats treated with CCl₄ and ethanol were analyzed with serum GOT and GPT level. The GOT and GPT levels of LAB group was lower than the level of CCl₄ and DDB group. Especially, compared with data of CCl₄ group, GPT activity showed statistically significant result in the significance level of p < 0.05. The LAB group treated with ethanol also showed lower level of GOT and GPT than the other control groups treated with ethanol. The triglyceride level of serum decreased more in a group treated special materials (DDB and LAB group) than ethanol group. As well, the effect of LAB on the antifatigue has been investigated. The animals (10/group) were divided into 4 groups (untreated group, Carrier group, Red-ginseng group, LAB group). Each group was given carrier (0.9 ㎎/0.2 ㎖), red ginseng extract (200 ㎎/㎏), and mixture of LAB (10<SUP>11</SUP>/0.2 ㎖). Special materials were given for three weeks. After finishing treating through oral, horizontal wire test, rotarod test, and forced swimming test were performed. The time of resistance to fatigue of the group, fed with mixture of LAB, was longer than the time when mice treated with red-ginseng that the effect was already revealed. The result of this study revealed that LAB could decrease hepatocelluar injury compared with rats treated orally with CCl₄ and ethanol, and could also decrease fatigue.

목차

INTRODUCTION
MATERIALS AND METHODS
RESULTS AND DISCUSSION
CONCLUSION
ACKNOWLEDGEMENTS
REFERENCES

참고문헌 (4)

참고문헌 신청

함께 읽어보면 좋을 논문

논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!

이 논문의 저자 정보

이 논문과 함께 이용한 논문

최근 본 자료

전체보기

댓글(0)

0

UCI(KEPA) : I410-ECN-0101-2009-513-016602054